Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Vladimir P. Torchilin
Keynote Presentation
Vladimir P. Torchilin, Northeastern University, United States

Tumor therapy, especially in the case of multidrug resistant cancers, could be significantly enhanced by using siRNA down-regulating the production of proteins, which are involved in cancer cell resistance, such as Pgp or survivin. Even better response could be achieved is such s [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Esmaiel Jabbari
Keynote Presentation
Esmaiel Jabbari, University of South Carolina, United States

A major contributing factor to mortality in cancer patients is relapse after therapy, and developing resistance. Cancer recurrence and resistance is related to the existence of a very small population of initiating stem cells (CSCs) in the tumor tissue with high expression of ATP [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Vladimir Muzykantov
Keynote Presentation
Vladimir Muzykantov, University of Pennsylvania the Perelman School of Medicine, United States

Endothelial cells lining the vascular lumen represent an important therapeutic target in many dangerous maladies. Some of them have no effective pharmacotherapy, at least in part due to inadequate drug delivery to intended site of action. Coupling drugs and carriers with specific [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Joe E. Springer
Keynote Presentation
Joe E. Springer, University of Kentucky, United States

Traumatic brain injury (TBI) is a leading cause of long-term impairments in higher cognitive function. Ongoing destructive secondary injury events occur minutes to days after the initial insult characterized by a cascade of pervasive biochemical and pathophysiological stressors i [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Eugenia V Gurevich
Keynote Presentation
Eugenia V Gurevich, Vanderbilt University, United States

Arrestins were discovered as the key proteins responsible for the shutoff of the G protein-dependent signaling by G protein-coupled receptors (GPCRs). Later it was discovered that arrestins regulate multiple signaling pathways, including mitogen activated protein (MAP) kinase pat [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Georgina Kate Such
Oral Presentation
Georgina Kate Such, The University of Melbourne, Australia

Nanoparticle delivery systems have potential for biomedical applications due to the ability of the nanoparticles to better target diseased cells or tissue, and therefore optimise the therapeutic payload to a treatment site. Self- assembled polymeric carriers have generated partic [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Marcelle Machluf
Oral Presentation
Marcelle Machluf, Technion – Israel Institute of Technology, Israel

Targeted drug and gene delivery technologies, mostly for oncological applications, have been extensively investigated for more than three decades. With only seven passively-targeted systems and just two actively-targeted antibody-drug conjugates in oncological use, it seems, howe [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Natassa Pippa
Oral Presentation
Natassa Pippa, University of Athens, Greece

The aim of this investigation is to present the novel progress performed in recent years in the field of design and development of new nanocarriers used in pharmaceutical nanotechnology. Special attention is assigned to chimeric and multicompartment drug delivery systems. Chimeri [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Daniel Zucker
Oral Presentation
Daniel Zucker, NOF Europe GmbH, Germany

A lipid nanoparticle (LNP) composed of a series of disulfide bridge cleavable and pH-reponsive lipid-like materials (COATOSOME SS-E-P4C2) was developed as a platform of a gene delivery system. The LNP showed good stability in the serum. The tertiary amine and disulfide bridge of [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Selene Baschieri
Oral Presentation
Selene Baschieri, Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), Italy

Plant virus nanoparticles (pVNPs) might represent an ideal delivery tool in terms of biocompatibility and biodegradability. They have evolved to use plants as their reproductive hosts, and to this aim, have developed infection strategies very different from those adopted by their [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Elaine Frances Enright
Oral Presentation
Elaine Frances Enright, University College Cork, Israel

Once regarded obscure, the cohabitation of man and microbe has gained increasing recognition as a determinant of the health status of the host. To date, pharmacokinetic research at the host-microbe interface has been primarily directed towards effects on metabolism. Microbial bil [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Ilya Yakavets
Oral Presentation
Ilya Yakavets, Universite de Lorraine, France

Application of meta-tetra(hydroxyphenyl)chorin (mTHPC), one of the most potent photosensitizer (PS), in the photodynamic therapy (PDT) of solid tumors encounters several complications resulting from its insolubility in aqueous medium. It requires low light doses and concentration [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Mikhail V. Khvostov
Oral Presentation
Mikhail V. Khvostov, N.N. Vorozhtsov Institute of Organic Chemistry SB RAS, Russian Federation

Oral drug delivery is the most popular route because of the low expenses and long-term compliance. However, this introduction route has several limitations for drug molecules. Some of them are low water solubility and poor bioavailability. To overcome these limitations “hos [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Ali Dehshahri
Oral Presentation
Ali Dehshahri, Shiraz University of Medical Sciences, Iran (Islamic Republic of)

Targeted delivery of polymer-based nanoparticles has been considered as an efficient approach to transfer genetic materials into cells. Considering the over expression of integrin αVβ3 receptor on tumor cells and the presence of the binding site for tetraiodothyroaceti [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Mino R. Caira
Keynote Presentation
Mino R. Caira , University of Cape Town, South Africa

Significant reduction or elimination of unfavourable properties of both well-established drugs and new drug candidates (e.g. poor aqueous solubility, thermal instability, hygroscopicity) can often be achieved via relatively simple strategies such as co-crystallization with partne [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Gillian Hutcheon
Keynote Presentation
Gillian Hutcheon, Liverpool John Moores University, United Kingdom

Migraine is an extremely common, disabling condition which ruins the lives of millions of patients worldwide and is hard to treat effectively. Existing migraine medications are only partially effective, they have unwanted side effects and some patients are resistant to any curren [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Gerhard Winter
Oral Presentation
Gerhard Winter, LMU Munchen, Germany

A wide range of new data on recent work with solid and semisolid lipid based depot formulations will be presented. As an alternative to PLGA based implants, lipid based rods for long term delivery of protein drugs have been studied in detail. The depot systems consist only of bio [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Tomasz Osmalek
Oral Presentation
Tomasz Osmalek, Poznan University of Medical Sciences (PUMS), Poland

Gellan gum is a linear, anionic biopolymer produced by the bacteria Sphingomonas elodea. Its chain consists of a tetrasaccharide repeating unit of L-rhamnose, D-glucose and D-glucuronate. Due to the unique structure and beneficial properties, gellan is broadly described as a [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Marc Du Jardin
Oral Presentation
Marc Du Jardin, Janssen, Belgium

The Beerse developability groups provides physchem and formulation support to both discovery and toxicology teams within Janssen Belgium. In early discovery, it is essential to keep pace with the discovery teams and assure timely delivery of solubility results using Semi High Thr [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Yulia Svenskaya
Oral Presentation
Yulia Svenskaya, Saratov State University, Russian Federation

Porous calcium carbonate submicron particles are proposed as effective carriers for transdermal drug transportation. Administration of bioactive substances via skin appendages arouses a scientific interest regarding to reduced systemic toxicity in terms of targeted delivery. A dr [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Kira Astakhova
Oral Presentation
Kira Astakhova, University of Southern Denmark, Denmark

The Low Density Lipoprotein receptor (LDLR) is a cell surface expressed protein that binds and internalizes low density lipoprotein (LDL), resulting in cholesterol being made available to the cell. A method to stably over-express LDLR could result in an increased removal of LDL f [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Biana Godin
Oral Presentation
Biana Godin, Houston Methodist Research Institute, United States

Preterm labor, leading to preterm birth (birth prior to 37 weeks of pregnancy) is a leading cause of perinatal morbidity and mortality affecting estimated 15 million births worldwide annually. Since the fetus is not yet fully developed before 37 weeks of pregnancy, health problem [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Luis Jesus Villarreal Gomez
Oral Presentation
Luis Jesus Villarreal Gomez, Universidad Autonoma de Baja California, Mexico

Pulmonary arterial hypertension (PAH) is one of the main risk factors for cardiovascular, cerebrovascular and heart failure diseases, which are important causes of mortality in Mexico. In just six years, between 2000 and 2006, HBP prevalence increased 19.7% to one in three Mexica [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Gerald H Tomkin
Oral Presentation
Gerald H Tomkin, Beacon Hospital and Trinity College Dublin, Ireland

Type 2 diabetes is a complex disorder.  A relative rather than an absolute lack of insulin allows blood sugar to rise above normal even though the patients secret excess insulin. This is termed insulin resistance and is preceded by a hyperinsulinaemia phase where blood sugar [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Nataliya Storozhylova
Oral Presentation
Nataliya Storozhylova, University of Santiago de Compostela, Spain

Intra-articular (IA) administration of drugs is an appealing therapy for the effective treatment of joint diseases; however, challenging due to premature elimination of injected drugs and drug delivery systems (DDSs) from the synovial cavity. Aiming at increased retention and [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Hadrien Calmet
Oral Presentation
Hadrien Calmet, Barcelona Supercomputing Center (BSC-CNS), Spain

New treatment in aerosol medicine exhalation through the nose (ETN) is one of promising and comprehensive methods for Eosinophilic Chronic Rhinosinusitis (ECRS) with asthma. The patient inhales aerosol of inhaled corticosteroid (ICS) medicine from mouth using portable inhaler. Th [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Takahisa yamamoto
Oral Presentation
Takahisa yamamoto, National Institute of Technology, Gifu College, Japan

Recently patients who suffer Eosinophilic Chronic Rhinosinusitis with asthma (ECRS) have significantly increased in Asia. This disease has been recognized as an incurable disease, and its symptoms are multiple nasal polyps, excessive rhinorrhea, rhinostenosis and asthma. The diff [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Matej Dobravc Verbic
Oral Presentation
Matej Dobravc Verbic, University Medical Centre Ljubljana, Slovenia

Pancreatic cancer is the fourth most fatal cancer in both men and women. Patients usually remain asymptomatic until advanced stages of disease, and prognosis has not improved over the past 20 years. However, new treatment options for locally advanced and metastatic disease have e [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Marcelo Nacucchio
Oral Presentation
Marcelo Nacucchio, University of Buenos Aires, Argentina

New scaffolds and biomaterials will be presented with pharmaceutical characterization as well biological evaluation. For one bioceramic/polymeric new product clinical trials results will be presented. Prospectives technologies associated with this field of bone regeneration will [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Vandana B. Patravale
Oral Presentation
Vandana B. Patravale, Institute of Chemical Technology, India

Dementia (neurodegenerative ailments) accounts for over 50 million cases worldwide with estimated new 7.7 million cases every year. Neurodegenerative ailments associated progressive decline in clinical condition mainly results from poor transport of therapeutic actives across blo [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Lonchin Suguna
Oral Presentation
Lonchin Suguna, Central Leather Research Institute, India

Nowadays, gold nanoparticles (AuNPs) are gaining wide attention in several areas including research and development and medical fields. Certain polyphenols have the property of converting the Au3+ solution into AuNPs at an appropriate pH and at the same time binding to them. [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Monika Eniko Balint
Poster Presentation
Monika Eniko Balint, University of Pecs, Hungary

Blind docking has been widely used for fast mapping of binding sites on the entire surface of drug targets. Reliability of blind docking is limited by approximations of hydration models, simplified handling of molecular flexibility, and imperfect search algorithms. Wrap and  [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Ilya Yakavets
Poster Presentation
Ilya Yakavets, Universite de Lorraine, France

Due to their ability to carry anticancer drugs and generate localized heat when exposed to an alternating magnetic field, superparamagnetic iron oxide (SPIO) nanoparticles (NPs) can be used as multimodal cancer therapy agent by combining chemotherapy and hyperthermia. Fe3O4 nanop [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Pawel Brzuzan
Poster Presentation
Pawel Brzuzan, University of Warmia and Mazury in Olsztyn, Poland

The delivery of therapeutic snippets of RNA (mainly siRNA) to the right cells at the right time is an essential step in the RNA mediated therapeutics, that in fish has not been studied in sufficient detail. Here we report an efficient in vivo delivery of MiRNA92b-3p mimic to whit [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Jeong Kyu Bang
Poster Presentation
Jeong Kyu Bang, Korea Basic Science Institute, Korea, Republic of

We present on the first chemical synthesis of ultra-short pyrazole-arginine based antimicrobial peptidomimetics derived from the newly synthesized N-alkyl/aryl-pyrazole amino acids. Through systematic tuning of hydrophobicity, charge, and peptide length, we can obtain the shortes [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Joanna Jaworska
Poster Presentation
Joanna Jaworska, Polish Academy of Sciences, Poland

Caprolactone-based polymers are willingly used as a biodegradable materials with desirable properties. They are frequently used as a drug delivery systems for controlled release of different active substances like: antibiotics, growth factors, and hormones. They are mostly copoly [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Katarzyna Jelonek
Poster Presentation
Katarzyna Jelonek, Polish Academy of Sciences, Poland

Polymeric micelles have been widely studied and developed as drug carrier for targeting solid tumors. They are able to incorporate drugs of poor water solubility in the hydrophobic core while the hydrophilic corona provides biocompatibility and prolonged circulation in blood afte [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Hyung Jun Ahn,
Poster Presentation
Hyung Jun Ahn,, Korea Institute of Sceince and Technology, Korea, Republic of

The inherent or acquired resistance to paclitaxel and cisplatin, which are commonly used chemotherapeutic agents for ovarian cancer treatment, remains an important issue in chemotherapy of multidrug resistant ovarian cancer. Currently, it is still challenging to deal with the rec [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Attila Gacsi
Poster Presentation
Attila Gacsi, University of Szeged, Hungary

Dermal drug delivery systems are getting more attention nowadays because their application is beneficial in many conditions. Dermal application is advantageous due to a decrease in potential adverse reactions and the avoidance of first pass metabolism. However, the skin penetrati [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Sang Keun Ha
Poster Presentation
Sang Keun Ha, Korea Food Research Institute, Korea, Republic of

In this study, we evaluated the effects of EU on AGEs-induced renal disease and explored the possible underlying mechanisms using streptozotocin (STZ)-induced diabetic mice. STZ-induced diabetic mice received EU extract (200 mg/kg) orally for 6 weeks. EU treatment did not change [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Anayanti Arianto
Poster Presentation
Anayanti Arianto, University of Sumatera Utara, Indonesia

Background: Indomethacin is a potential nonsteroidal anti-inflammatory drugs (NSIDs), but it can cause gastrointestinal irritation if it is given orally. The delivery system of indomethacin through skin can avoid the side effect, but the skin has a major barrier that is stra [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Ana Carolina Kogawa
Poster Presentation
Ana Carolina Kogawa, Univ Estadual Paulista – UNESP, Brazil

Rifaximin, an oral antimicrobial, acts locally in the gastrointestinal tract with minimal systemic adverse effects. It is mainly used for the treatment of hepatic encephalopathy, but also in cases of ulcerative colitis, irritable bowel syndrome, travelers' diarrhea and acute [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Prashant G. Upadhaya
Poster Presentation
Prashant G. Upadhaya, Institute of Chemical Technology, India

Developing effective methods for drug delivery into the brain is one of the major challenges faced today. In the current arena the research fraternity is mostly involved in the drug discovery and chemical modification of pre-existing molecules which certainly do not facilitate en [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Ivana Hrebickova
Poster Presentation
Ivana Hrebickova, Charles University, Czech Republic

Psychostimulants, including methamphetamine (MA), have neurotoxic effect, especially, if they are targeting CNS during its critical periods of development. Prenatal/neonatal MA exposure (5 mg/ml/kg) during gestation and/or lactation makes adult rats more sensitive to acute inject [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Mario Jug
Workshop
Mario Jug, University of Zagreb, Croatia (Hrvatska)

Mucosal route of drug delivery is recognised as suitable alternative to conventional drug administration routes (i.e. oral and parenteral), providing the possibility of more efficient local therapy with reduced systemic drug exposure as well as alternative application route for d [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - El Hassane Larhrib
Keynote Presentation
El Hassane Larhrib, University of Huddersfield, United Kingdom

Inhaled therapy plays an important role in the management of airway diseases such as, asthma and chronic obstructive pulmonary disease (COPD). Peak inhalation flow has been considered for so many years by the inhalation scientists as the most important parameter governing drug de [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Michal Abrahamowicz
Keynote Presentation
Michal Abrahamowicz, McGill University, Canada

Recent large governmental initiatives e.g. Canadian Drug Safety and Effectiveness Network or the US Sentinel program, emphasize the need to assess the real-life effectiveness and safety of drugs in populationbased studies. Increasing availability of large databases, generated thr [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Irina Ermolina
Oral Presentation
Irina Ermolina, De Montfort University School of Pharmacy, United Kingdom

Hydrogels have attracted considerable attention due to their capability to be used for numerous pharmaceutical and biomedical applications (i.e. drug delivery systems, contact lenses and wound dressings). Hydrogels are swellable polymeric materias capable of imbibing a large amou [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Chaodong Wu
Oral Presentation
Chaodong Wu, Texas A&M University, United States

Obesity is an ongoing pandemic which serves a causal factor of a wide range of metabolic diseases such as type 2 diabetes, non-alcoholic fatty liver disease, and atherosclerotic cardiovascular diseases. Accumulating evidence has suggested inflammation as a factor underlying the p [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Csaba Heteny
Oral Presentation
Csaba Heteny, University of Pecs, Hungary

Originally, computational blind docking (BD) was introduced as a fast approach for finding binding positions and conformations of ligand molecules via scanning the entire surface of target molecules. BD can find not only primary binding sites but also allosteric or prerequisite o [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Guo-Ping Zhou
Oral Presentation
Guo-Ping Zhou, Guangxi Academy of Sciences, China

Polysialic acid (polySia) is a novel glycan that posttranslationally modifies neural cell adhesion molecules (NCAMs) in mammalian cells. Up-regulation of polySia-NCAM expression is associated with tumor progression in many metastatic cancers. Both members of the ST8Sia family of [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Sergey Bachurin
Oral Presentation
Sergey Bachurin, Russian Academy of Sciences, Russian Federation

Alzheimer’s disease (AD) is characterized by a chronic and progressive neurodegenerative process resulting from the intracellular and extracellular accumulation of fibrillary proteins: beta-amyloid and hyperphosphorylated Tau. Over accumulation of these aggregates leads to [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Maya Bar-Zeev
Oral Presentation
Maya Bar-Zeev, Technion – Israel Institute of Technology, Israel

Gastrointestinal cancers are the third leading cause of cancer-related deaths worldwide. Moreover, multidrug resistance (MDR) mediated by ATP-dependent efflux transporters remains a dominant obstacle toward curative cancer therapy. Furthermore, most chemotherapeutic agents are li [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Ursula Thevarajah
Oral Presentation
Ursula Thevarajah, University of Huddersfield, United Kingdom

The aim of this study was to engineer a novel lactose carrier in the presence of an inflating agent in the crystallisation medium to produce large hollow spherical carrier particles for inhalation. Hollow spherical Engineered carrier and tomahawk shaped commercial carrier (contro [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Faiza Naseer
Oral Presentation
Faiza Naseer, University of Huddersfield, United Kingdom

Most dry powder inhalers are formulated by mixing micronized drugs with lactose as a carrier. Lactose is the major element in terms of weights in a dry powder inhaler formulation therefore, any changes in its physicochemical properties can affect drug detachment from the surface [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Lourdes Amable Vega Rasgado
Oral Presentation
Lourdes Amable Vega Rasgado, Escuela Nacional de Ciencias Biologicas del Instituto Politecnico Nacional, Mexico

people suffer from epilepsy, and 30% of them do not respond with traditional antiepileptic drugs. Thus, different strategies for seizures control in such patients are required. Seizures are the result of an imbalance between excitatory and inhibitory impulses on the central nervo [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Hakim Bangun,
Oral Presentation
Hakim Bangun,, University of Sumatera Utara, Indonesia

Most pharmaceutical capsules are made from  gelatine. These material dissolve in the low pH gastric juices in the stomach. But, for certain purposes capsules are designed to pass through the stomach and into the intestine before dissolving,  such products are described [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Enise Ece Gurdal
Oral Presentation
Enise Ece Gurdal, Yeditepe University, Turkey

Cancer, characterized by uncontrolled cell growth, causes the death of about 7 million patients each year. Malignant cells can spread all over the body through the lymphatic and the circulatory systems. Side effects of chemotherapeutic drugs being used for cancer treatment affect [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - K.V.R.N.S.Ramesh
Oral Presentation
K.V.R.N.S.Ramesh, RAK Medical & Health Sciences University, United Arab Emirates

The present study was  carried out to evaluate the usefulness of sulfobutyl ether β-cyclodextrin (SBE7-β-CD), [captisol], in increasing the dissolution rate of tenoxicam. The efficacy of captisol in increasing the dissolution when  compared  with beta cyc [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Hemant K. S. Yadav
Oral Presentation
Hemant K. S. Yadav, RAK Medical & Health Science University, United Arab Emirates

During the presentation the presenter will be talking about the formulation and evaluation of self microemulsifying system of a poorly water soluble drug. The talk will include what are self microemulsifying systems and how to prepare them along with their advantages. Approaches [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Ana Carolina Kogawa
Oral Presentation
Ana Carolina Kogawa, Univ Estadual Paulista – UNESP, Brazil

Rifaximin, an oral antimicrobial, is mainly used for the treatment of hepatic encephalopathy, but also in cases of ulcerative colitis, irritable bowel syndrome, Clostridium difficile, travelers' diarrhea and acute diarrhea. Rifaximin does not present microbiological methods d [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Tatyana V. Leshina
Oral Presentation
Tatyana V. Leshina, Voevodsky Institute of Chemichal Kinetics and Combustion SB RAS, Russian Federation

The difference in the medical properties of the enantiomers of many chiral drugs is a well-known fact. This is a big problem, since most drugs are still used in the form of racemates. The latter is connected with the difficulties of separation. One of the most prominent represent [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Mehrdad Azarmi Aghajan
Oral Presentation
Mehrdad Azarmi Aghajan, Shahid Beheshti University, Iran (Islamic Republic of)

In RMT route, NPs are designed to target specific cells and cause cell death or induce a significant change in cellular behavior. Receptor?targeted therapeutics are developed to restrict the distribution of toxic drugs to only the pathologic cells, thus diminishing collateral sid [....] » Read More

Speaker at Global Conference on Pharmaceutics and Drug Delivery Systems 2018 - Hassan Saeiahan
Oral Presentation
Hassan Saeiahan, Iran University of Medical science, Iran (Islamic Republic of)

Methotrexate, abbreviated MTX and formerly known as amethopterin, is an antineoplastic, antimetabolite and antifulate drug. It is used in treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. Disturbances in the normal redox stat [....] » Read More

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