Alpha and Delta coronaviruses spread worldwide claiming >634000 lives and secondary multidrug-resistant infections were found a risk factor specifically in ICU patients containing carbapenem-resistant Acinetobacter baumannii, Pseudomonas aeruginosa, Enterococcus faecium and Kl [....] » Read More
Wounds remain a huge public health issue, at least in terms of morbidity and long-term disability, throughout the world, especially in developing countries. Plant-derived natural products are significant as sources of medicinal agents and models for the design of new remedies. Th [....] » Read More
Exosomes are a heterogeneous group of nano-sized natural membrane vesicles released from various cells and exist in body fluids. Exosomes act as carriers with many kinds of bioactive molecules (e.g., proteins, lipids, and nucleic acids) to play an important role in cell-cell comm [....] » Read More
Title : New excipient to formulate poorly soluble APIs
Rajendran Arunagiri, Eastman, United States
One of the toughest challenges facing the drug development today is poor solubility of the API. It is estimated that 70%+ of the APIs in drug development pipeline are poorly soluble in water. There are several approaches to this problem with many requiring processes such as spray [....] » Read More
Title : Limiting factors in implementing pharmacovigilance principles in the elderly
Hana Hassan, University of Bristol, United Kingdom
The overarching aim of pharmacovigilance is to ensure the safe and effective usage of medication across the population and optimise medicines through holistic considerations. However, within the heterogeneous elderly population, a number of unique factors are at play, limiting th [....] » Read More
Title : Intellection of molecular drug delivery models -an ayurvedic perspective
Ashtavaidyan Dr. E.T. Krishnan Mooss, Vaidyaratnam Group , India
Ayurveda is a traditional healthcare system of Indian medicine since ancient times. Several drugs have been developed and practiced from Ayurveda since ancient times to modern practice as ‘tradition to trend’. Charaka Samhita, Sushruta Samhita (~400 BC–200 [....] » Read More
Title : Comparison of dexmedetomidine and propofol with ketofol in sedation of candidates for cataract surgery
Alireza Kamali, Arak University of Medical Sciences, Iran (Islamic Republic of)
Introduction: Cataract is the most common cause of vision loss in the world and about 30 to 40 million people in the world are scientifically blind, about 45% of which is cataract. A cataract is one of the most common surgeries performed in the elderly. The purpose of prescribing [....] » Read More
Title : Interdependent antioxidant therapy in covid-19 and other critical diseases
Richard Z. Cheng, Cheng Integrative Health Center, United States
Cytokine storm has recently been recognized as the key pathology responsible for the severe symptoms of Covid-19 and other viruses and non-viral agents. The underlying biochemical cause of cytokine storms is excessive oxidative stress. Cytokine storm and its associated oxidative [....] » Read More
Title : Multi-detection of pharmaceutical contamination in environment
Andreia Freitas, INIAV and REQUIMTE, Portugal
The constant release of veterinary and human pharmaceutical drugs as active compounds or metabolites to the environment can result in the presence of undesirable contaminants in the ecosystems. Such anthropogenic contaminants can be discharged into the environment through wastewa [....] » Read More