Nanomaterials have been widely tested in vitro and in small-order animal studies for decades. Results have shown greater tissue growth, decreased bacteria growth, and inhibited inflammation. However, few studies exist examining human tissue response to nanomaterials. This presentation presents a cohort study of nano implants inserted into humans. In particular, one study includes the implantation of nanotextured spinal implants into over 14,000 patients over the past 5 years. Results demonstrated no cases of infections or other implant failures which is significantly better than statistics on conventional spinal implants which have up to 20% failure rates. This study will further explain that nano implants mimic the natural nano texture of bone itself and possess surface energy that can competitively increase the adsorption of proteins known to promote osteoblast (bone-forming cells) functions, decrease bacteria functions, and limit inflammatory cell functions. As such, this presentation will cover a few human clinical studies on nano implants showing improved human health.
Audience Take Away Notes:
- How nanomaterials are improving health in humans
- Specific human clinical data with nanomaterials
- What is the mechanism by which nanomaterials improve tissue growth, limit infection, and reduce inflammation