Title : ShamacureR a new topical gel as an alternative treatment for skin diseases in animals and its economic value
Abstract:
The effects of Ganoderma species-based petrolatum paste (gel) preparation against Dermatophilosis and other mixed fungal infective organisms in goats was investigated. Twelve adult (12) goats of different sexes, and all affected with dermatological conditions were purchased from Maiduguri cattle market, and were then serially numbered 1-12 for easy identification. They were divided into four (4) groups; A=1-3, B= 4-6, C= 7-9 and D= 10-12, each group comprise 3goats/ group. Initial microbial analysis of scab and skin scrapings from the lesion on the infected goat’s skin indicating the disease was mainly caused by Dermatophylus condolences (bacteria) and in addition, other fungal organisms such as Rhyzopus oryzae, Aspergillus niger and Penicillin sp were all identified. Preparations of 2.2 mg/ml, 4.4 mg/ml and 6.7 mg/ml of the powdered Ganoderma sp. were made in 450 ml petrolatum jelly. These were used for topical application on lesions on infected goats in groups A, B and C respectively, while goats in group D were treated with CharmilR, and goats in this served as positive control. The infected goats were treated by daily (bid) application of the Ganoderma species-based petrolatum paste for a period of one week. Result from the study showed that the petrolatum based Ganoderma specie (ShamacureR) treated the entire skin lesion in all the treated groups as against CharmilR treated group. The skin integrity of the ShamacureR treated groups after a week of daily application as compared to the CharmilR treated group. Similar studies were carried out in mange in sheep, and it showed similar results at However it was noted that response to treatment was concentration dependent and faster in 6.7 mg/ml than other lower concentrations, hence the choice of this concentration in formulating ShamacureR.
