Isolation and evaluation of antioxidant and cytotoxic activity of 2',4'-dihydroxy-3',5'-dimethyl-6'-methoxychalcone from the ethyl acetate extract of the leaves of Syzygium balsameum (Wight) Wall. ex Walp

Title : Isolation and evaluation of antioxidant and cytotoxic activity of 2',4'-dihydroxy-3',5'-dimethyl-6'-methoxychalcone from the ethyl acetate extract of the leaves of Syzygium balsameum (Wight) Wall. ex Walp

Abstract:

Syzygium balsameum Wight is shrubs or trees of the Myrtaceae family. The present study reports on the based-onand isolation of a flavonoid 2',4'-dihydroxy-3',5'-dimethyl-6'-methoxychalconefrom the leaves of Syzygium balsameum and evaluation of the antioxidant and cytotoxic property. The compound is characterized by the spectroscopic analysis UV, IR, EIMS, ¹H, ¹³CNMR, COSY, HMBC, and HSQC. The compound2',4'-dihydroxy-3',5'-dimethyl-6'-methoxychalcone is first time isolated from the Syzygium balsameum wight and exhibited good antioxidant and cytotoxic property compare to the extract and the standard.

Biography:

Dr. Rozina Parul studied Pharmacy at the Jahangirnagar University, Bangladesh and graduated MS in 2005. She has joined at Department of Pharmacy of Gono University, Savar, Bangladesh as a Lecturer in 2007 and currently working as Associate Professor. She received her PhD degree in 2025 at the same institution. underlining the topic: “Exploration of Phytoconstituents and evaluation of bioactivities of Syzygium balsameum and Syzygium formosum”. She has published 16 research articles in national and international journal.