Isolation and evaluation of antioxidant and cytotoxic activity of 2',4'-dihydroxy-3',5'-dimethyl-6'-methoxychalcone from the ethyl acetate extract of the leaves of Syzygium balsameum (Wight) Wall. ex Walp

Syzygium balsameum Wight is shrubs or trees of the Myrtaceae family. The present study reports on the based-onand isolation of a flavonoid 2',4'-dihydroxy-3',5'-dimethyl-6'-methoxychalconefrom the leaves of Syzygium balsameum and evaluation of the antioxidant and cytotoxic property. The compound is characterized by the spectroscopic analysis UV, IR, EIMS, ¹H, ¹³CNMR, COSY, HMBC, and HSQC. The compound2',4'-dihydroxy-3',5'-dimethyl-6'-methoxychalcone is first time isolated from the Syzygium balsameum wight and exhibited good antioxidant and cytotoxic property compare to the extract and the standard.