Abstract
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This research explores the creation of a novel exosome delivery platform, termed Exo-ITC, tailored for use in dermatology. Exosomes, as extracellular vesicles, are pivotal in intercellular communication and exhibit substantial therapeutic potential in regenerative medicine and dermatological treatments. The study aims to fabricate a bilayer fibrous system capable of controlled exosome loading and release, enhancing collagen production and skin regeneration. The system is developed using electrospinning techniques, integrating exosomes into a bilayer fibrous structure. Comprehensive characterization is conducted, including morphological analysis (scanning electron microscopy), particle size distribution (dynamic light scattering), stability (thermogravimetric analysis), and exosome release efficiency. The findings offer critical insights into the feasibility and therapeutic potential of the Exo-ITC system for skin care applications. This innovative system is expected to address various dermatological conditions, utilizing the regenerative and therapeutic properties of exosomes. Overall, this research marks a significant step forward in advancing topical therapies for skin health and regeneration.
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