Abstract:
This research explores the creation of a novel exosome delivery platform, termed Exo-ITC, tailored for use in dermatology. Exosomes, as extracellular vesicles, are pivotal in intercellular communication and exhibit substantial therapeutic potential in regenerative medicine and dermatological treatments. The study aims to fabricate a bilayer fibrous system capable of controlled exosome loading and release, enhancing collagen production and skin regeneration. The system is developed using electrospinning techniques, integrating exosomes into a bilayer fibrous structure. Comprehensive characterization is conducted, including morphological analysis (scanning electron microscopy), particle size distribution (dynamic light scattering), stability (thermogravimetric analysis), and exosome release efficiency. The findings offer critical insights into the feasibility and therapeutic potential of the Exo-ITC system for skin care applications. This innovative system is expected to address various dermatological conditions, utilizing the regenerative and therapeutic properties of exosomes. Overall, this research marks a significant step forward in advancing topical therapies for skin health and regeneration.
Biography:
Dr. Luis Villarreal is a research professor at the Faculty of Engineering Sciences and Technology, Autonomous University of Baja California, Tijuana, Baja California, Mexico, member of the National System of Researchers SNII-CONAHCyT Level 2, and a member of the academic body Applied Bioengineering "In Consolidation". To date, Dr. Villarreal has published 51 indexed articles, with a total of 1,134 citations in Scopus. Currently, Research and Graduate Coordinator of the Faculty, General Coordinator of MyDAUD-Multicampus. He has participated in more than 70 national and international conferences. Founder and Editor-in-Chief of the Revista de Ciencias Tecnológicas (RECIT) (only 5 official ones at UABC), organizing president of the main international conferences of the Faculty FCITEC and member of the editorial committee of important publishers such as Bentham, MDPI, Hindawi, Wiley. He is a member of the editorial advisory board of the journal “Current Drug Delivery” and a referee for more than 210 articles participating in publishers such as Elsevier, Wiley, Springer, MDPI and Hindawi among others. He also participates as an evaluator of research projects for funding in Mexico, Italy, Malaysia and Peru. He has contributed to the generation of human resources with 10 undergraduate theses, 10 master's theses and 5 doctoral theses. His research lines in the area of Biomaterials are in Tissue Engineering, Drug Release Systems and Biotechnology, among others. The improvement in the treatment of infants is his primary objective.
