Toxicokinetics, a pivotal facet of pharmacology, intricately scrutinizes the absorption, distribution, metabolism, and excretion (ADME) processes of toxic substances within the biological system. Commencing with absorption, these pharmacologically relevant toxins ingress into the bloodstream, undergoing subsequent distribution to various tissues. The crux of metabolism follows, where toxic compounds undergo transformation into either less deleterious forms or potentially more pharmacologically active metabolites. Sophisticated methodologies, including pharmacokinetic modeling and cutting-edge analytical techniques, are deployed by researchers to unravel the intricate dynamics inherent in toxicokinetics. These discernments play a pivotal role in shaping efficacious detoxification strategies and informing therapeutic interventions, thereby fostering a comprehensive approach to the pharmaceutical management of toxic exposures. Such advancements empower the pharmaceutical industry to develop innovative solutions for mitigating the impact of toxic substances, ultimately promoting the well-being of individuals and communities.
Title : Ectopically expressed olfactory receptors as an untapped family of drug targets and discovery of agonists and antagonists of OR51E1, an understudied G protein-coupled receptor
Vladlen Slepak, University of Miami Miller School of Medicine, United States
Title : Managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Analytical strategies for solid-state forms in drug development
Maria Cristina Gamberini, University of Modena e Reggio Emilia, Italy
Title : Understanding drug transport in plasma: The role of protein binding
Saad Tayyab, UCSI University, Malaysia
Title : Innovative development and delivery of biologics for chronic obstructive pulmonary disease
Yong Xiao Wang, Albany Medical College, United States
Title : Search for novel biomarkers and therapeutic targets for inflammatory disease
Madhav Bhatia, University of Otago, New Zealand
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through de-sign-inspired biotech- & biopharma-driven applications and upgraded business mar-keting to secure the human healthcare and biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : Design and evaluation of exo-itc: A bilayer fibrous system for controlled exosome delivery in dermatological applications
Luis Jesus Villarreal Gomez, FCITEC - Universidad AutĂłnoma de Baja California, Mexico
Title : Abuse-deterrent dosage form technique utilizing a fusion of innovative pharmaceuticals and ion exchange resin
Bhupendra Gopalbhai Prajapati, Parul University, India
Title : Macitentan/tadalafil combination– An additional value in pharmacotherapy of pulmonary arterial hypertension
Miroslav Radenkovic, University of Belgrade, Serbia