Toxicokinetics, a pivotal facet of pharmacology, intricately scrutinizes the absorption, distribution, metabolism, and excretion (ADME) processes of toxic substances within the biological system. Commencing with absorption, these pharmacologically relevant toxins ingress into the bloodstream, undergoing subsequent distribution to various tissues. The crux of metabolism follows, where toxic compounds undergo transformation into either less deleterious forms or potentially more pharmacologically active metabolites. Sophisticated methodologies, including pharmacokinetic modeling and cutting-edge analytical techniques, are deployed by researchers to unravel the intricate dynamics inherent in toxicokinetics. These discernments play a pivotal role in shaping efficacious detoxification strategies and informing therapeutic interventions, thereby fostering a comprehensive approach to the pharmaceutical management of toxic exposures. Such advancements empower the pharmaceutical industry to develop innovative solutions for mitigating the impact of toxic substances, ultimately promoting the well-being of individuals and communities.
Title : Medical liver biopsy: Toward a personalized approach
Consolato M Sergi, Universities of Alberta and Ottawa, Canada
Title : Emerging formulation and delivery applications of vitamin E TPGS
Andreas M Papas, Antares Health Products, United States
Title : Ectopically expressed olfactory receptors as an untapped family of drug targets and discovery of agonists and antagonists of OR51E1, an understudied G protein-coupled receptor
Vladlen Slepak, University of Miami Miller School of Medicine, United States
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through design-inspired biotech- & biopharma-driven applications and upgraded business marketing to secure the human healthcare and biosafety
Sergey Suchkov, The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Title : Managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Innovative development and delivery of biologics for chronic obstructive pulmonary disease
Yong Xiao Wang, Albany Medical College, United States
Title : Macitentan/tadalafil combination– An additional value in pharmacotherapy of pulmonary arterial hypertension
Miroslav Radenkovic, University of Belgrade, Serbia
Title : Mathematical modeling the disc diffusion test: Antibacterial activity of copper-doped SnO2
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Genetic keys and nano locks: Unlocking personalized medicine
Srividya Narayanan, Northeastern University, United States
Title : Design and evaluation of exo-itc: A bilayer fibrous system for controlled exosome delivery in dermatological applications
Luis Jesus Villarreal Gomez, FCITEC - Universidad AutĂłnoma de Baja California, Mexico