Clinical trials are a critical phase in the drug development process, providing essential data on the safety and efficacy of new therapies. During clinical trials, drugs undergo rigorous testing across multiple phases, starting with small groups of healthy volunteers to assess safety and dosage. As the trial progresses, larger groups of patients are involved to evaluate the drug's effectiveness in treating specific conditions. Clinical trials also play a key role in understanding the pharmacokinetics and pharmacodynamics of new drugs, which helps in determining optimal dosages and administration methods. Advances in clinical trial design, such as adaptive trials and decentralized trials, are improving efficiency and patient recruitment. In addition, the integration of innovative drug delivery systems in clinical trials ensures that therapies are targeted precisely, offering better treatment outcomes and fewer side effects. Clinical trials remain the gold standard for bringing safe and effective new drugs to market.
Title : Principles and standards for managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : From marker to mechanism: Ligand discovery enables functional analysis of OR51E1, an ectopic olfactory receptor, in prostate cancer
Vladlen Slepak, University of Miami School of Medicine, United States
Title : Hydrogen sulfide in sepsis: From bench to bedside
Madhav Bhatia, University of Otago, New Zealand
Title : Tailored cellular environments to enable drug design
Lan Wang, Paretor LLC, United States
Title : Development of novel drug delivery pathways enabled by perillyl alcohol (NEO100), A monoterpene with multifaceted biomedical applications
Axel H Schonthal, University of Southern California, United States
Title : A NAMs-compatible mechanopharmacological model of drug penetration in the urinary bladder
Kunal Sharma, Swisss Federal Institute of Technology Lausanne, Switzerland
Title : Application of quality by design for pulmonary liposomes: Preliminary study to nano in-microparticle
Lucas Amaral Machado, University of Sao Paulo State – UNESP, Brazil
Title : Integrated Raman, SERS and computational approaches for the study of bioactive molecules in pharmaceutical chemistry
Maria Cristina Gamberini, University of Modena and Reggio Emilia, Italy
Title : The impact of metal-decorated polymeric nanodots on proton relaxivity
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Hepatotoxic botanicals-shadows of pearls
Consolato M Sergi, University of Alberta, Canada