Drug delivery routes and challenges play a significant role in determining the effectiveness of pharmaceutical treatments. Different routes, such as oral, intravenous, transdermal, and inhalational, offer unique benefits but also come with specific obstacles. Oral delivery is widely used for its convenience but is often hindered by issues like poor bioavailability and first-pass metabolism. Intravenous routes provide rapid action, though they require professional administration and carry infection risks. Transdermal delivery offers controlled, long-term release but faces limitations related to skin permeability. Inhalational routes are effective for targeting the lungs but present challenges in dosing accuracy and formulation stability. Each of these Drug Delivery Routes and Challenges requires innovative solutions to improve drug efficacy, safety, and patient adherence, with advances in targeted and nanotechnology-based drug delivery systems helping to overcome many of these barriers.
Title : Principles and standards for managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : From marker to mechanism: Ligand discovery enables functional analysis of OR51E1, an ectopic olfactory receptor, in prostate cancer
Vladlen Slepak, University of Miami School of Medicine, United States
Title : Hydrogen sulfide in sepsis: From bench to bedside
Madhav Bhatia, University of Otago, New Zealand
Title : Tailored cellular environments to enable drug design
Lan Wang, Paretor LLC, United States
Title : Development of novel drug delivery pathways enabled by perillyl alcohol (NEO100), A monoterpene with multifaceted biomedical applications
Axel H Schonthal, University of Southern California, United States
Title : A NAMs-compatible mechanopharmacological model of drug penetration in the urinary bladder
Kunal Sharma, Swisss Federal Institute of Technology Lausanne, Switzerland
Title : Application of quality by design for pulmonary liposomes: Preliminary study to nano in-microparticle
Lucas Amaral Machado, University of Sao Paulo State – UNESP, Brazil
Title : Integrated Raman, SERS and computational approaches for the study of bioactive molecules in pharmaceutical chemistry
Maria Cristina Gamberini, University of Modena and Reggio Emilia, Italy
Title : The impact of metal-decorated polymeric nanodots on proton relaxivity
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Hepatotoxic botanicals-shadows of pearls
Consolato M Sergi, University of Alberta, Canada