Cellular Targeting and Intracellular Delivery

• Drug Targeting and Design
• Targeted Drug Delivery System

Cellular targeting is one way to actively target solely diseased tissue in the body is to know the nature of a receptor on the cell for which the drug will be targeted and then utilization of cell-specific ligands will allow the nanoparticle to bind specifically to the cell that has the complementary receptor.

Intracellular delivery enables efficient drug delivery into various types of cells and it is a long-term studied topic in modern biotechnology. It is a critical process in many cellular-level studies, such as cellular drug therapy, gene editing delivery, and a series of biomedical research applications.

Targeted Drug Delivery System:A targeted drug delivery system is a particular form of drug delivery where the drug is released specifically to its site of action and not to the target organs, tissues, or cells.

Drug Targeting and Design: Drug targeting can be defined as the ability of a drug molecule to accumulate in the target organ or tissue specifically, so that the concentration of the drug will be high at the disease, while in non-target organs and tissues, its concentration is low, preferably, below the certain minimal level so as to prevent any toxic effects. Drug targeting can control the non-specific toxic effect of conventional drug delivery.

Drug design is also known as rational drug design or simply rational design. It is a new process of producing new medications based on the knowledge of a biological target.