Safety Pharmacology is a crucial discipline focused on evaluating the potential adverse effects of pharmaceutical compounds on physiological functions. Within this domain, pharmacodynamics plays a central role, examining how drugs interact with the body and elicit their effects. It involves the study of drug-receptor interactions, signal transduction pathways, and the subsequent physiological responses. Understanding pharmacodynamics is paramount in assessing the safety profile of a drug, as it enables the identification of potential risks and adverse reactions. Comprehensive investigations into drug-receptor binding kinetics, dose-response relationships, and the impact on vital organ systems contribute to ensuring the overall safety and efficacy of pharmaceutical interventions. In safety pharmacology, a nuanced comprehension of pharmacodynamics aids in predicting and mitigating undesirable effects, allowing for the development of safer and more targeted therapeutic interventions. Rigorous assessments of drug-induced alterations in physiological functions empower researchers and regulators to make informed decisions, ultimately enhancing the safety profile of pharmaceuticals before they reach the market.
Title : Medical liver biopsy: Toward a personalized approach
Consolato M Sergi, Universities of Alberta and Ottawa, Canada
Title : Emerging formulation and delivery applications of vitamin E TPGS
Andreas M Papas, Antares Health Products, United States
Title : Ectopically expressed olfactory receptors as an untapped family of drug targets and discovery of agonists and antagonists of OR51E1, an understudied G protein-coupled receptor
Vladlen Slepak, University of Miami Miller School of Medicine, United States
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through de-sign-inspired biotech- & biopharma-driven applications and upgraded business mar-keting to secure the human healthcare and biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : Managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Innovative development and delivery of biologics for chronic obstructive pulmonary disease
Yong Xiao Wang, Albany Medical College, United States
Title : Mathematical modeling the disc diffusion test: Antibacterial activity of copper-doped SnO2
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Antibody-proteases as translational tools of the next-step generation to be applied for biopharmacy-related and precision medical practice
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : Storage stability and solution binding affinity of an fc-fusion mimetic
Hanieh Khalili, University of East London, United Kingdom
Title : Macitentan/tadalafil combination– An additional value in pharmacotherapy of pulmonary arterial hypertension
Miroslav Radenkovic, University of Belgrade, Serbia