A medication that has been ingested alters chemically and metabolically. The medicine is now less readily available at the body's ultimate site of action as a result of these modifications. For instance, some medications may not be productive when taken orally but may be useful when given intravenously. The optimal method of drug delivery helps to achieve the medicine's full therapeutic benefit by reducing or avoiding these alterations. Additionally, when given through a specific route as opposed to another, some medications are more fully absorbed. 100% bioavailability is achieved when the medication is administered intravenously. There are various factors that influence a drug's preferred method of administration. These include drug characteristics, the targeted location of action, the rate and amount of absorption from the drug administration site, and the drug administration site itself. The effect of digestive juices and first pass metabolism, the speed with which the required reaction is achieved in an emergency or during normal therapy, the need for precise dosing, the patient's condition and compliance. The Various routes of Drug Administration includes:
1. Gastrointestinal route
a) Oral route
b) Sublingual route
c) Buccal route
d) Rectal route
2. Parenteral route
a) Intradermal
b) Sub-cutaneous
c) Intramuscular
d) Intravenous
3.Topical route
a) Transdermal patches
b) Instillations
c) Irrigation or Douching
d) Epidermic and enepidermic routes
e) Throat paints
4. Inhalation route
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Consolato M Sergi, Universities of Alberta and Ottawa, Canada
Title : Development of novel drug delivery pathways enabled by perillyl alcohol (NEO100), A monoterpene with multifaceted biomedical applications
Axel H Schonthal, University of Southern California, United States
Title : From marker to mechanism: Ligand discovery enables functional analysis of OR51E1, an ectopic olfactory receptor, in prostate cancer
Vladlen Slepak, University of Miami, United States
Title : The impact of metal-decorated polymeric nanodots on proton relaxivity
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Principles and standards for managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model based on design-inspired biotech- & biopharma-driven applications to secure the human healthcare and biosafety
Sergey Suchkov, N D Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : R&D consultancy at the medicines discovery catapult: De-risking drug discovery for innovators
Adriana Gambardella, Medicine Discovery Catapult, United Kingdom
Title : Biocompatible synthesis of non crystalline iron oxide nanoparticles with stable colloidal properties
Lan Wang, Paretor LLC, United States
Title : Hydrogen sulfide in sepsis: From bench to bedside
Madhav Bhatia, University of Otago, New Zealand
Title : Biocompatibility and subcutaneous host response to silk fibroin–chitosan composite plugs: Progress toward biodegradable implant materials
Luis Jesus Villarreal Gomez, Universidad Autónoma de Baja California, Mexico