The use of Radioisotopes is important in pharmaceutical research and development (R&D). They are frequently used in non-clinical and clinical studies for the development of compounds for different therapeutic areas, such as central nervous system (CNS) diseases (e.g., Dementia, Alzheimer’s disease (AD), and Parkinson’s disease), oncology, and metabolic diseases (e.g., diabetes mellitus). Pharmaceutical companies invest a lot of time and money in research on new treatment strategies for diseases with a high medical need, such as oncology and metabolic diseases. A large number of drugs fails during development due to toxicity and/or the lack of efficacy (Kola, I, 2008). Several attempts are being made to improve this, such as obtaining a better understanding of the pathophysiology of diseases, development of robust animal models, the application of biomarkers, development of pharmacokinetic (PK) - pharmacodynamic (PD) models, and the application of non-invasive techniques such as positron emission tomography (PET) in an early stage of development.
Title : Principles and standards for managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : From marker to mechanism: Ligand discovery enables functional analysis of OR51E1, an ectopic olfactory receptor, in prostate cancer
Vladlen Slepak, University of Miami School of Medicine, United States
Title : Hydrogen sulfide in sepsis: From bench to bedside
Madhav Bhatia, University of Otago, New Zealand
Title : Tailored cellular environments to enable drug design
Lan Wang, Paretor LLC, United States
Title : Development of novel drug delivery pathways enabled by perillyl alcohol (NEO100), A monoterpene with multifaceted biomedical applications
Axel H Schonthal, University of Southern California, United States
Title : A NAMs-compatible mechanopharmacological model of drug penetration in the urinary bladder
Kunal Sharma, Swisss Federal Institute of Technology Lausanne, Switzerland
Title : Application of quality by design for pulmonary liposomes: Preliminary study to nano in-microparticle
Lucas Amaral Machado, University of Sao Paulo State – UNESP, Brazil
Title : Integrated Raman, SERS and computational approaches for the study of bioactive molecules in pharmaceutical chemistry
Maria Cristina Gamberini, University of Modena and Reggio Emilia, Italy
Title : The impact of metal-decorated polymeric nanodots on proton relaxivity
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Hepatotoxic botanicals-shadows of pearls
Consolato M Sergi, University of Alberta, Canada