A prodrug is a strategic innovation in biopharmaceutics designed to enhance the absorption, distribution, and delivery of therapeutic agents within the human body. This ingenious approach involves the administration of an inactive precursor that undergoes a biotransformation to the active drug form, either enzymatically or non-enzymatically, after administration.
In biopharmaceutics, prodrugs address challenges such as poor solubility, stability, or limited bioavailability of certain drugs. By converting the active compound into a prodrug, these limitations can be overcome, leading to improved therapeutic outcomes. Prodrugs also allow for targeted drug delivery, minimizing potential side effects and enhancing patient compliance.
The versatility of prodrugs spans various drug classes, including analgesics, antivirals, and anticancer agents. This approach exemplifies the continual evolution of pharmaceutical science in optimizing drug performance and patient well-being. As a key player in the realm of biopharmaceutics, prodrugs pave the way for more efficient and precise drug delivery strategies in the field of medicine.
Consolato M Sergi
Universities of Alberta and Ottawa, Canada
Vladlen Slepak
University of Miami Miller School of Medicine, United States
Andreas M Papas
Antares Health Products, United States
Sergey Suchkov
The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian FederationSubmit your abstract Today
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