Preformulation Studies
  • Organoleptic and Bulk Characters
  • Solubility analysis
  • Stability analysis

It is a phase of research and development to characterize the physical and chemical properties of a drug molecule in order to develop a safe, effective, and stable dosage form.

Usually, Preformulation studies are laboratory studies which are used to determine the characteristics of active substance and excipients that may influence the formulation and process design and performance. It has been described as “Learning before doing”.

A major area of Preformulation studies includes:

Organoleptic and Bulk Characters: These include

  • Crystallinty and Polymorphism
  • Hygroscopicity
  • Fine particle characterization
  • Powder flow properties

Solubility analysis: This includes:

  • Ionization constant-PKa
  • pH solubility profile
  • Common ion effect-Ksp
  • Thermal effects
  • Solubilization
  • Partition co-efficient
  • Dissolution

Stability analysis: This includes:

  • Stability in toxicology formulations
  • Solution stability
  • pH rate profile
  • Solid-state stability
  • Bulk stability
  • Compatibility
Committee Members
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Sergey Suchkov

Sergey Suchkov

Sechenov University and Moscow Engineering Physical Institute, Russian Federation
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Marino Nebuloni

Marino Nebuloni

Parma University, Italy
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Esmaiel Jabbari

Esmaiel Jabbari

University of South Carolina, United States
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Paul Millner

Paul Millner

University of Leeds, United Kingdom
PDDS 2021 Speakers
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Jan Versijpt

Jan Versijpt

University Hospital Brussels, Belgium
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Madhav Bhatia

Madhav Bhatia

University of Otago, New Zealand
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Stefanie Santos

Stefanie Santos

University Hospital Zurich, Switzerland
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Dmitry Ustyuzhanin

Dmitry Ustyuzhanin

National Medical Research Center of Cardiology, Russian Federation
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Anna Caprifico

Anna Caprifico

Kingston University, United Kingdom
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Annalisa Dalmoro

Annalisa Dalmoro

University of Salerno, Italy

Submit your abstract Today

Watsapp