Preformulation Studies
- Organoleptic and Bulk Characters
- Solubility analysis
- Stability analysis
It is a phase of research and development to characterize the physical and chemical properties of a drug molecule in order to develop a safe, effective, and stable dosage form.
Usually, Preformulation studies are laboratory studies which are used to determine the characteristics of active substance and excipients that may influence the formulation and process design and performance. It has been described as “Learning before doing”.
A major area of Preformulation studies includes:
Organoleptic and Bulk Characters: These include
- Crystallinty and Polymorphism
- Hygroscopicity
- Fine particle characterization
- Powder flow properties
Solubility analysis: This includes:
- Ionization constant-PKa
- pH solubility profile
- Common ion effect-Ksp
- Thermal effects
- Solubilization
- Partition co-efficient
- Dissolution
Stability analysis: This includes:
- Stability in toxicology formulations
- Solution stability
- pH rate profile
- Solid-state stability
- Bulk stability
- Compatibility
Committee Members
Vladlen Slepak
University of Miami Miller School of Medicine, United States
Yong Xiao Wang
Albany Medical College, United States
Consolato M Sergi
Universities of Alberta and Ottawa, Canada
Huiqin Yang
ICON Clinical Research Ltd, United KingdomSubmit your abstract Today
Title : The impact of metal-decorated polymeric nanodots on proton relaxivity
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Hepatotoxic botanicals-shadows of pearls
Consolato M Sergi, Universities of Alberta and Ottawa, Canada
Title : Exploring classical ayurvedic drugs in hypertension
Prashant Bhokardankar, Datta Meghe Ayurved College, India
Title : Principles and standards for managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model based on design-inspired biotech- & biopharma-driven applications to secure the human healthcare and biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : Antibody proteases as translational tools of the next step generation to be applied for biopharmacy related and precision medical practice
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : Easily injectable, organic solvent free self assembled hydrogel platform for endoscope mediated gastrointestinal polypectomy
Hitasha Vithalani , IIT Gandhinagar, India
Title : Cognitivevoice: Novel machine learning model leveraging acoustic features to predict future cognitive decline in Parkinson’s Disease
Aadya Daga, Hamilton High School, United States
Title : Platelet-activating factor-receptor pathway mediates solar radiation-induced extracellular vesicle release in human keratinocytes
Ravi P Sahu, Wright State University, United States