A pharmacophore is a molecular framework that elucidates the essential features required for a ligand to bind to its target receptor with high affinity and specificity. It represents a spatial arrangement of key functional groups critical for biological activity. Pharmacophore modelling plays a pivotal role in drug design and discovery by identifying crucial interactions between ligands and target proteins. This concept aids medicinal chemists in rational drug design, allowing them to optimize molecular structures for enhanced potency and selectivity. Pharmacophore-based virtual screening accelerates the identification of potential drug candidates, streamlining the drug development process. By understanding the essential elements for biological activity, researchers can design molecules with improved pharmacokinetic properties and reduced side effects. In summary, pharmacophores serve as invaluable tools in the quest for novel therapeutic agents, facilitating the creation of more effective and safer drugs.
Vladlen Slepak
University of Miami, United States
Axel H Schonthal
University of Southern California, United States
Consolato M Sergi
University of Alberta, Canada
Huiqin Yang
ICON Clinical Research Ltd, United Kingdom
Madhav Bhatia
University of Otago, New Zealand
Luis Jesus Villarreal Gomez
Universidad Autónoma de Baja California, Mexico
Saad Tayyab
UCSI University, Malaysia
Anil Pareek
Anand Pharmacy College, India
Lan Wang
Paretor LLC, United States
Helen Cho
Samyang Biopharm Corporation, Korea, Republic ofSubmit your abstract Today
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Axel H Schonthal, University of Southern California, United States
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