Pharmacokinetic evaluation in pregnancy is a critical aspect of ensuring maternal and fetal health during the administration of medications. The physiological changes occurring during pregnancy, such as altered blood flow, increased plasma volume, and changes in liver metabolism, can significantly impact drug absorption, distribution, metabolism, and elimination. Understanding these alterations is essential for determining appropriate dosage regimens and minimizing potential risks to both the mother and the developing fetus. Researchers employ various techniques, including pharmacokinetic modeling and population studies, to assess the dynamic changes in drug disposition throughout pregnancy. Additionally, the unique challenges posed by the potential teratogenicity of certain drugs require careful consideration and evaluation. Monitoring maternal drug levels, adjusting dosages, and assessing potential fetal exposure are integral components of ensuring therapeutic efficacy while mitigating potential harm. This comprehensive evaluation contributes to the development of evidence-based guidelines for drug use in pregnant women, promoting safer pharmacotherapy during this critical period.
Title : Ectopically expressed olfactory receptors as an untapped family of drug targets and discovery of agonists and antagonists of OR51E1, an understudied G protein-coupled receptor
Vladlen Slepak, University of Miami Miller School of Medicine, United States
Title : Managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Analytical strategies for solid-state forms in drug development
Maria Cristina Gamberini, University of Modena e Reggio Emilia, Italy
Title : Understanding drug transport in plasma: The role of protein binding
Saad Tayyab, UCSI University, Malaysia
Title : Innovative development and delivery of biologics for chronic obstructive pulmonary disease
Yong Xiao Wang, Albany Medical College, United States
Title : Search for novel biomarkers and therapeutic targets for inflammatory disease
Madhav Bhatia, University of Otago, New Zealand
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through de-sign-inspired biotech- & biopharma-driven applications and upgraded business mar-keting to secure the human healthcare and biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : Design and evaluation of exo-itc: A bilayer fibrous system for controlled exosome delivery in dermatological applications
Luis Jesus Villarreal Gomez, FCITEC - Universidad AutĂłnoma de Baja California, Mexico
Title : Abuse-deterrent dosage form technique utilizing a fusion of innovative pharmaceuticals and ion exchange resin
Bhupendra Gopalbhai Prajapati, Parul University, India
Title : Macitentan/tadalafil combination– An additional value in pharmacotherapy of pulmonary arterial hypertension
Miroslav Radenkovic, University of Belgrade, Serbia