The study of Pharmacodynamics focuses on how medications affect the body. The drug's interaction with tissue receptors found within cell membranes or intracellular fluid is the most frequent method. The amount of the activating medication (the "agonist") affects the degree of receptor activation and the ensuing biological reaction. The dose-response curve, which charts the medication dose (or concentration) against its effect, provides an explanation for this relationship. Patient characteristics (such as age and illness) and the availability of additional medications that compete with it for binding at the same receptor (such as receptor "antagonists") might have an impact on this crucial pharmacodynamic interaction. Some medications that operate on the same receptor (or tissue) differ in their ability to produce large biological reactions (i.e., their "efficacy") and the dosage needed to produce such responses (i.e., their "potency"). Drug receptors can be categorised according to how selectively they react to various medicines. Drugs can occasionally cause a diminished reaction when receptors or bodily systems are exposed to them repeatedly
Title : Principles and standards for managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : From marker to mechanism: Ligand discovery enables functional analysis of OR51E1, an ectopic olfactory receptor, in prostate cancer
Vladlen Slepak, University of Miami School of Medicine, United States
Title : Hydrogen sulfide in sepsis: From bench to bedside
Madhav Bhatia, University of Otago, New Zealand
Title : Tailored cellular environments to enable drug design
Lan Wang, Paretor LLC, United States
Title : Development of novel drug delivery pathways enabled by perillyl alcohol (NEO100), A monoterpene with multifaceted biomedical applications
Axel H Schonthal, University of Southern California, United States
Title : A NAMs-compatible mechanopharmacological model of drug penetration in the urinary bladder
Kunal Sharma, Swisss Federal Institute of Technology Lausanne, Switzerland
Title : Application of quality by design for pulmonary liposomes: Preliminary study to nano in-microparticle
Lucas Amaral Machado, University of Sao Paulo State – UNESP, Brazil
Title : Integrated Raman, SERS and computational approaches for the study of bioactive molecules in pharmaceutical chemistry
Maria Cristina Gamberini, University of Modena and Reggio Emilia, Italy
Title : The impact of metal-decorated polymeric nanodots on proton relaxivity
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Hepatotoxic botanicals-shadows of pearls
Consolato M Sergi, University of Alberta, Canada