Pharmaceutical toxicology stands as a specialized domain dedicated to unraveling and evaluating the potential negative impacts of pharmaceutical products on living organisms. At its core, this field plays a pivotal role in ensuring the safety of drugs before they enter the market, maintaining a vigilant watch over their effects throughout their entire lifespan.
A crucial facet of pharmaceutical toxicology delves into the exploration of toxicokinetics and toxicodynamics of drugs. The former scrutinizes how the body absorbs, distributes, metabolizes, and excretes drugs, shedding light on their systemic effects. Meanwhile, toxicodynamics investigates the intricate mechanisms through which drugs induce toxic effects at the cellular and molecular levels.
During the initial phases of drug development, preclinical toxicology studies come into play, aiming to pinpoint potential risks and establish safe dosage levels. Utilizing animal models, these studies simulate human responses and gauge the impact of pharmaceuticals on various organs and physiological systems.
Post-marketing surveillance emerges as yet another pivotal element of pharmaceutical toxicology, involving continuous monitoring of drugs post-public availability. This ongoing scrutiny aids in identifying any unforeseen adverse reactions or long-term effects that might not have surfaced during preclinical studies.
Pharmaceutical toxicologists work hand in hand with diverse disciplines, including pharmacology and clinical medicine, fostering a comprehensive evaluation of the safety profile of pharmaceuticals. Their collaborative efforts significantly contribute to regulatory decisions, steering the development and utilization of drugs with an unwavering commitment to prioritizing patient safety and well-being.
Title : The impact of metal-decorated polymeric nanodots on proton relaxivity
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Hepatotoxic botanicals-shadows of pearls
Consolato M Sergi, Universities of Alberta and Ottawa, Canada
Title : Exploring classical ayurvedic drugs in hypertension
Prashant Bhokardankar, Datta Meghe Ayurved College, India
Title : Principles and standards for managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model based on design-inspired biotech- & biopharma-driven applications to secure the human healthcare and biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : A unique role and and impact of catalytic antibodies (abzymes) in clinical practice: A novel strategy for predicting and preventing relapse in chronic autoimmune conditions
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : The promise of nanotechnology in personalized & precision medicine: Drug discovery & development being partnered with nanotechnologies via the revolution at the nanoscale
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : The promising future of the unique translational tool to manage beta-cell population renewal and regeneration to secure the post-diabetic period
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : Easily injectable, organic solvent free self assembled hydrogel platform for endoscope mediated gastrointestinal polypectomy
Hitasha Vithalani , IIT Gandhinagar, India