Pharmaceutical Research is the development and research of novel drugs in the Pharmaceutical industry. Understanding the condition and choosing a target—typically a cell's receptor site—that a medication molecule might be able to alter are the first steps in the procedure. The majority of the time, scientists develop new molecules or genetically edit existing ones in order to discover a small number of the top hundred compounds. The top candidates are put to the test in the lab to see whether they are redistributed to the right site of action, and are delivered to the correct site of absorption, metabolization, and excretion without being overly hazardous. Before human clinical trials can start, candidates are examined in the lab and on animals in order to make improvements to performance. Phase 1 studies evaluate how the medication candidate affects a limited group of healthy people. A candidate's effectiveness and short-term adverse effects are assessed in phase 2 trials on a small number of people, whereas phase 3 trials examine these qualities on a larger group of participants. Companies remove candidates from trials at each stage if they are not functioning as anticipated or if their future commercial possibilities make them unprofitable. Even though they are referred to be "failures," the corporation frequently withdraws for business-related reasons.
Title : Medical liver biopsy: Toward a personalized approach
Consolato M Sergi, Universities of Alberta and Ottawa, Canada
Title : Macitentan/tadalafil combination– An additional value in pharmacotherapy of pulmonary arterial hypertension
Miroslav Radenkovic, University of Belgrade, Serbia
Title : Ectopically expressed olfactory receptors as an untapped family of drug targets and discovery of agonists and antagonists of OR51E1, an understudied G protein-coupled receptor
Vladlen Slepak, University of Miami Miller School of Medicine, United States
Title : Mathematical modeling the disc diffusion test: Antibacterial activity of copper-doped SnO2
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Emerging formulation and delivery applications of Vitamin E TPGS
Andreas M Papas, Antares Health Products, United States
Title : The promise of nanotechnology in personalized & precision medicine: Drug discovery & development being partnered with nanotechnologies via the revolution at the nanoscale
Sergey Suchkov, The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through design-inspired biotech- & biopharma-driven applications and upgraded business marketing to secure the human healthcare and biosafety
Sergey Suchkov, The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Title : Design and evaluation of exo-itc: A bilayer fibrous system for controlled exosome delivery in dermatological applications
Luis Jesus Villarreal Gomez, FCITEC - Universidad AutĂłnoma de Baja California, Mexico
Title : Antibody-proteases as translational tools of the next-step generation to be applied for biopharmacy-related and precision medical practice
Sergey Suchkov, The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Title : Understanding drug transport in plasma: The role of protein binding
Saad Tayyab, UCSI University, Malaysia