Pharmaceutical drug testing is the meticulous exploration of a compound's safety, efficacy, and potential side effects, marking a pivotal phase in the journey from discovery to market. This intricate process unfolds in a series of carefully designed trials, each serving a distinct purpose in unravelling the compound's impact on the human body. The journey begins with preclinical testing, where researchers delve into the compound's behaviour in the laboratory and animal models. This phase unveils insights into safety profiles, potential dosage ranges, and initial efficacy.
Upon successful preclinical evaluations, the compound progresses to clinical trials, a multi-phase endeavour involving human subjects. Phase 1 focuses on safety and dosage, Phase 2 delves into efficacy, and Phase 3 expands to larger populations, further validating the drug's effectiveness and monitoring for rare side effects. Regulatory bodies meticulously review the accumulated data, assessing the compound's risk-benefit profile before granting approval for market release. Post-marketing surveillance continues the scrutiny, ensuring ongoing safety and efficacy monitoring.
The evolution of pharmaceutical drug testing mirrors a meticulous orchestration of scientific inquiry, ethical considerations, and regulatory diligence. Each trial, from petri dish to patient, contributes to the collective endeavour of bringing safe and effective medications to those in need.
Title : Medical liver biopsy: Toward a personalized approach
Consolato M Sergi, Universities of Alberta and Ottawa, Canada
Title : Macitentan/tadalafil combination– An additional value in pharmacotherapy of pulmonary arterial hypertension
Miroslav Radenkovic, University of Belgrade, Serbia
Title : Ectopically expressed olfactory receptors as an untapped family of drug targets and discovery of agonists and antagonists of OR51E1, an understudied G protein-coupled receptor
Vladlen Slepak, University of Miami Miller School of Medicine, United States
Title : Mathematical modeling the disc diffusion test: Antibacterial activity of copper-doped SnO2
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Emerging formulation and delivery applications of Vitamin E TPGS
Andreas M Papas, Antares Health Products, United States
Title : The promise of nanotechnology in personalized & precision medicine: Drug discovery & development being partnered with nanotechnologies via the revolution at the nanoscale
Sergey Suchkov, The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through design-inspired biotech- & biopharma-driven applications and upgraded business marketing to secure the human healthcare and biosafety
Sergey Suchkov, The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Title : Design and evaluation of exo-itc: A bilayer fibrous system for controlled exosome delivery in dermatological applications
Luis Jesus Villarreal Gomez, FCITEC - Universidad AutĂłnoma de Baja California, Mexico
Title : Antibody-proteases as translational tools of the next-step generation to be applied for biopharmacy-related and precision medical practice
Sergey Suchkov, The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Title : Understanding drug transport in plasma: The role of protein binding
Saad Tayyab, UCSI University, Malaysia