Peptides are now being explored as diagnostic equipment in addition to being utilised as medications to treat a variety of medical diseases. Peptides have lately been used for therapeutics to target medication molecules to particular types of cells (such as immune cells, cancer cells), therefore reducing the adverse effects of the medicines. To deliver the treatment to the target cells (in this example, cancer cells), which express greater levels of a particular receptor that detects the carrier peptide, the drug is in this case coupled to the carrier peptide. As a consequence, the medicine targets the damaged cells it is meant to treat without harming healthy cells. Additionally, peptides are being created to facilitate medication transport across the blood-brain barrier and intestinal mucosa barrier (IMB). These peptides enhance drug transport via the IMB and BBB via the paracellular routes and were generated from intercellular junction proteins such occludins, claudins, and cadherins. In order to improve the porosity of the paracellular pathways of the barriers, it is theorised that the peptides affect protein-protein interactions in the intercellular junctions of the IMB and BBB. It has been demonstrated that these modulator peptides improve the transport of big proteins like 65 kDa albumin as well as tiny molecules and medium-sized peptides to the brain. This technique may enhance the transport of therapeutic and diagnostic peptides and proteins to the brain in the future.
Title : The impact of metal-decorated polymeric nanodots on proton relaxivity
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Hepatotoxic botanicals-shadows of pearls
Consolato M Sergi, Universities of Alberta and Ottawa, Canada
Title : Exploring classical ayurvedic drugs in hypertension
Prashant Bhokardankar, Datta Meghe Ayurved College, India
Title : Principles and standards for managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model based on design-inspired biotech- & biopharma-driven applications to secure the human healthcare and biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : A unique role and and impact of catalytic antibodies (abzymes) in clinical practice: A novel strategy for predicting and preventing relapse in chronic autoimmune conditions
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : The promise of nanotechnology in personalized & precision medicine: Drug discovery & development being partnered with nanotechnologies via the revolution at the nanoscale
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : The promising future of the unique translational tool to manage beta-cell population renewal and regeneration to secure the post-diabetic period
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : Easily injectable, organic solvent free self assembled hydrogel platform for endoscope mediated gastrointestinal polypectomy
Hitasha Vithalani , IIT Gandhinagar, India