Nucleic acid drugs represent a groundbreaking frontier in biopharmaceutics, offering innovative approaches to treat various diseases at the genetic level. These drugs harness the power of nucleic acids, such as RNA and DNA, to target specific genes associated with illnesses. In the realm of biopharmaceutics, nucleic acid drugs hold immense potential for precision medicine, allowing tailored treatments based on individual genetic profiles.
The development of nucleic acid drugs has opened avenues for tackling genetic disorders, cancers, and infectious diseases with unprecedented precision. Their mechanism involves modulating gene expression, silencing harmful genes, or correcting genetic mutations. Despite initial challenges, advancements in delivery systems and formulations have enhanced the stability and bioavailability of nucleic acid drugs.
Biopharmaceutics researchers are actively exploring the therapeutic possibilities of antisense oligonucleotides, siRNA, and gene-editing technologies. As these nucleic acid drugs progress through clinical trials, they signify a paradigm shift in personalized medicine and hold promise for transforming the landscape of biopharmaceutical interventions.
Title : The impact of metal-decorated polymeric nanodots on proton relaxivity
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil