Lyophilisation, commonly known as freeze-drying, plays a pivotal role in the field of biopharmaceutics, revolutionizing the preservation of sensitive biological materials. This sophisticated process involves freezing a substance and then removing the frozen solvent through sublimation, resulting in a stable, dry product with an extended shelf life.
In biopharmaceutics, lyophilisation is instrumental in preserving the integrity of delicate biomolecules such as proteins, enzymes, and vaccines. This method mitigates the risks of degradation and maintains the bioactivity of these substances, ensuring their efficacy upon reconstitution. The versatility of lyophilisation makes it an indispensable tool in pharmaceuticals, allowing for the development of injectable drugs, oral tablets, and other dosage forms.
Beyond stability, lyophilisation addresses challenges associated with transportation and storage, particularly for biopharmaceuticals that require stringent temperature control. This process facilitates the creation of lightweight, transportable formulations without compromising the therapeutic potential of the drug.
Yong Xiao Wang
Albany Medical College, United States
Consolato M Sergi
Universities of Alberta and Ottawa, Canada
Vladlen Slepak
University of Miami Miller School of Medicine, United States
Andreas M Papas
Antares Health Products, United States
Bernd Blobel
University of Regensburg, Germany
Huiqin Yang
ICON Clinical Research Ltd, United Kingdom
Srividya Narayanan
Northeastern University, United States
Maria Richards Brown
University College London, United Kingdom
Rassa Pegahi
UPSA, France
Hanieh Khalili
University of East London, United KingdomSubmit your abstract Today
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