Gene delivery systems researchers are vital contributors to pharmaceutics, working to develop and refine methods for transporting genetic material into cells safely and effectively. Their primary challenge is to design vectors that can efficiently deliver DNA, RNA, or gene-editing components while avoiding degradation and minimizing immune reactions. Researchers explore a broad spectrum of delivery platforms, ranging from viral vectors like adenoviruses and lentiviruses to non-viral carriers such as liposomes, polymeric nanoparticles, and lipid-based systems. By studying the physicochemical properties and biological interactions of these carriers, they seek to enhance gene transfer efficiency, targeting specificity, and biocompatibility.
Gene delivery systems researchers focus on overcoming biological barriers such as enzymatic degradation, immune clearance, and cellular uptake limitations. They conduct detailed in vitro and in vivo studies to understand the pharmacodynamics, biodistribution, and safety profiles of gene delivery systems. These efforts support the translation of experimental therapies into clinical practice, often involving collaboration with molecular biologists, clinicians, and regulatory experts. The integration of cutting-edge gene editing technologies like CRISPR-Cas9 further expands their scope, enabling precise genome modifications. Through continuous innovation and interdisciplinary work, gene delivery systems researchers are paving the way for next-generation gene therapies that hold the potential to transform patient care and address unmet medical needs in pharmaceutics.
Title : Ectopically expressed olfactory receptors as an untapped family of drug targets and discovery of agonists and antagonists of OR51E1, an understudied G protein-coupled receptor
Vladlen Slepak, University of Miami Miller School of Medicine, United States
Title : Managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Analytical strategies for solid-state forms in drug development
Maria Cristina Gamberini, University of Modena e Reggio Emilia, Italy
Title : Understanding drug transport in plasma: The role of protein binding
Saad Tayyab, UCSI University, Malaysia
Title : Innovative development and delivery of biologics for chronic obstructive pulmonary disease
Yong Xiao Wang, Albany Medical College, United States
Title : Search for novel biomarkers and therapeutic targets for inflammatory disease
Madhav Bhatia, University of Otago, New Zealand
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through de-sign-inspired biotech- & biopharma-driven applications and upgraded business mar-keting to secure the human healthcare and biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : Design and evaluation of exo-itc: A bilayer fibrous system for controlled exosome delivery in dermatological applications
Luis Jesus Villarreal Gomez, FCITEC - Universidad AutĂłnoma de Baja California, Mexico
Title : Abuse-deterrent dosage form technique utilizing a fusion of innovative pharmaceuticals and ion exchange resin
Bhupendra Gopalbhai Prajapati, Parul University, India
Title : Macitentan/tadalafil combination– An additional value in pharmacotherapy of pulmonary arterial hypertension
Miroslav Radenkovic, University of Belgrade, Serbia