Excipients play a pivotal role in the field of biopharmaceutics, serving as essential components in drug formulations. These inert substances, often referred to as formulation aids, not only enhance the stability and bioavailability of active pharmaceutical ingredients (APIs) but also contribute to the overall safety and efficacy of pharmaceutical products.
In biopharmaceutics, excipients are carefully selected to facilitate drug absorption, distribution, metabolism, and excretion. They can influence drug release profiles, solubility, and permeability, playing a crucial role in optimizing the therapeutic performance of a formulation. Excipients also contribute to the physical and chemical stability of biopharmaceuticals, ensuring their integrity throughout the manufacturing, storage, and administration processes.
Furthermore, excipients may aid in overcoming formulation challenges, such as poor drug solubility or instability, ultimately improving the overall pharmacokinetics of the drug. As the field of biopharmaceutics continues to evolve, the strategic use of excipients remains integral to the development of innovative drug delivery systems, fostering advancements in therapeutic efficacy and patient outcomes.
Title : Ectopically expressed olfactory receptors as an untapped family of drug targets and discovery of agonists and antagonists of OR51E1, an understudied G protein-coupled receptor
Vladlen Slepak, University of Miami Miller School of Medicine, United States
Title : Managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Analytical strategies for solid-state forms in drug development
Maria Cristina Gamberini, University of Modena e Reggio Emilia, Italy
Title : Understanding drug transport in plasma: The role of protein binding
Saad Tayyab, UCSI University, Malaysia
Title : Innovative development and delivery of biologics for chronic obstructive pulmonary disease
Yong Xiao Wang, Albany Medical College, United States
Title : Search for novel biomarkers and therapeutic targets for inflammatory disease
Madhav Bhatia, University of Otago, New Zealand
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through de-sign-inspired biotech- & biopharma-driven applications and upgraded business mar-keting to secure the human healthcare and biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : Design and evaluation of exo-itc: A bilayer fibrous system for controlled exosome delivery in dermatological applications
Luis Jesus Villarreal Gomez, FCITEC - Universidad AutĂłnoma de Baja California, Mexico
Title : Abuse-deterrent dosage form technique utilizing a fusion of innovative pharmaceuticals and ion exchange resin
Bhupendra Gopalbhai Prajapati, Parul University, India
Title : Macitentan/tadalafil combination– An additional value in pharmacotherapy of pulmonary arterial hypertension
Miroslav Radenkovic, University of Belgrade, Serbia