Excipients play a pivotal role in the field of biopharmaceutics, serving as essential components in drug formulations. These inert substances, often referred to as formulation aids, not only enhance the stability and bioavailability of active pharmaceutical ingredients (APIs) but also contribute to the overall safety and efficacy of pharmaceutical products.
In biopharmaceutics, excipients are carefully selected to facilitate drug absorption, distribution, metabolism, and excretion. They can influence drug release profiles, solubility, and permeability, playing a crucial role in optimizing the therapeutic performance of a formulation. Excipients also contribute to the physical and chemical stability of biopharmaceuticals, ensuring their integrity throughout the manufacturing, storage, and administration processes.
Furthermore, excipients may aid in overcoming formulation challenges, such as poor drug solubility or instability, ultimately improving the overall pharmacokinetics of the drug. As the field of biopharmaceutics continues to evolve, the strategic use of excipients remains integral to the development of innovative drug delivery systems, fostering advancements in therapeutic efficacy and patient outcomes.
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Consolato M Sergi, Universities of Alberta and Ottawa, Canada
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Axel H Schonthal, University of Southern California, United States
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Vladlen Slepak, University of Miami, United States
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Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
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Bernd Blobel, University of Regensburg, Germany
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model based on design-inspired biotech- & biopharma-driven applications to secure the human healthcare and biosafety
Sergey Suchkov, N D Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : R&D consultancy at the medicines discovery catapult: De-risking drug discovery for innovators
Adriana Gambardella, Medicine Discovery Catapult, United Kingdom
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Lan Wang, Paretor LLC, United States
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Madhav Bhatia, University of Otago, New Zealand
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Luis Jesus Villarreal Gomez, Universidad Autónoma de Baja California, Mexico