Excipients play a pivotal role in the field of biopharmaceutics, serving as essential components in drug formulations. These inert substances, often referred to as formulation aids, not only enhance the stability and bioavailability of active pharmaceutical ingredients (APIs) but also contribute to the overall safety and efficacy of pharmaceutical products.
In biopharmaceutics, excipients are carefully selected to facilitate drug absorption, distribution, metabolism, and excretion. They can influence drug release profiles, solubility, and permeability, playing a crucial role in optimizing the therapeutic performance of a formulation. Excipients also contribute to the physical and chemical stability of biopharmaceuticals, ensuring their integrity throughout the manufacturing, storage, and administration processes.
Furthermore, excipients may aid in overcoming formulation challenges, such as poor drug solubility or instability, ultimately improving the overall pharmacokinetics of the drug. As the field of biopharmaceutics continues to evolve, the strategic use of excipients remains integral to the development of innovative drug delivery systems, fostering advancements in therapeutic efficacy and patient outcomes.
Title : Development of novel drug delivery pathways enabled by perillyl alcohol (NEO100), A monoterpene with multifaceted biomedical applications
Axel H Schonthal, University of Southern California, United States
Title : From marker to mechanism: Ligand discovery enables functional analysis of OR51E1, an ectopic olfactory receptor, in prostate cancer
Vladlen Slepak, University of Miami, United States
Title : Hepatotoxic botanicals-shadows of pearls
Consolato M Sergi, University of Alberta, Canada
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model based on design-inspired biotech- & biopharma-driven applications to secure the human healthcare and biosafety
Sergey Suchkov, N D Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : R&D consultancy at the medicines discovery catapult: De-risking drug discovery for innovators
Adriana Gambardella, Medicine Discovery Catapult, United Kingdom
Title : Biocompatible synthesis of non crystalline iron oxide nanoparticles with stable colloidal properties
Lan Wang, Paretor LLC, United States
Title : Precision diagnostics: Effectiveness of innovative imaging technologies for early detection of lung cancers
Huiqin Yang, ICON Clinical Research Ltd, United Kingdom
Title : Principles and standards for managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Design and characterization of gum arabic buccal films for protein drug delivery
Krisztian Pamlenyi, University of Szeged, Hungary
Title : Advancing EGFR-targeting macrocyclic peptide-drug conjugates to target KRAS-mutant solid tumors: Design, synthesis, and preclinical evaluations
Akash Panja, Ariel University, Israel