Epigenetics is a captivating field of study within genetics that explores heritable changes in gene function and expression that occur without alterations to the underlying DNA sequence. This dynamic discipline investigates modifications such as DNA methylation, histone modification, and non-coding RNA, which influence gene activity and cellular functioning. Epigenetic mechanisms play a pivotal role in regulating diverse biological processes, including development, cellular differentiation, and responses to environmental stimuli.
Understanding epigenetic modifications is crucial for unravelling the complexities of diseases like cancer, where aberrant epigenetic patterns contribute to pathogenesis. The interplay between genetic and epigenetic factors provides a nuanced perspective on the heritability of traits and susceptibility to various conditions. Ongoing research in epigenetics holds promise for therapeutic interventions, as targeting specific epigenetic marks may offer innovative strategies for treating diseases with underlying epigenetic dysregulation. As technology advances, the exploration of the epigenome continues to deepen our understanding of how environmental factors shape gene expression and influence health outcomes.
Title : Principles and standards for managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : From marker to mechanism: Ligand discovery enables functional analysis of OR51E1, an ectopic olfactory receptor, in prostate cancer
Vladlen Slepak, University of Miami School of Medicine, United States
Title : Hydrogen sulfide in sepsis: From bench to bedside
Madhav Bhatia, University of Otago, New Zealand
Title : Tailored cellular environments to enable drug design
Lan Wang, Paretor LLC, United States
Title : Development of novel drug delivery pathways enabled by perillyl alcohol (NEO100), A monoterpene with multifaceted biomedical applications
Axel H Schonthal, University of Southern California, United States
Title : A NAMs-compatible mechanopharmacological model of drug penetration in the urinary bladder
Kunal Sharma, Swisss Federal Institute of Technology Lausanne, Switzerland
Title : Application of quality by design for pulmonary liposomes: Preliminary study to nano in-microparticle
Lucas Amaral Machado, University of Sao Paulo State – UNESP, Brazil
Title : Integrated Raman, SERS and computational approaches for the study of bioactive molecules in pharmaceutical chemistry
Maria Cristina Gamberini, University of Modena and Reggio Emilia, Italy
Title : The impact of metal-decorated polymeric nanodots on proton relaxivity
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Hepatotoxic botanicals-shadows of pearls
Consolato M Sergi, University of Alberta, Canada