Pharmacodynamics is the branch of pharmacology that explores drug issues like how drugs interact with the body at the molecular, cellular, and systemic levels to produce their therapeutic effects. Understanding pharmacodynamics is crucial for optimizing drug therapy and minimizing adverse effects. At the molecular level, drugs bind to specific receptors, initiating a cascade of events that can either enhance or inhibit physiological processes.
Cellular pharmacodynamics delves into the impact of drugs on individual cells, influencing cellular functions such as enzyme activity, ion channel modulation, and gene expression. Systemic pharmacodynamics considers the overall effect of drugs on organ systems and the entire organism, taking into account factors like absorption, distribution, metabolism, and excretion.
The study of pharmacodynamics is pivotal in tailoring drug regimens to individual patients, ensuring efficacy while minimizing side effects. It also plays a vital role in drug development, helping researchers design compounds with optimal therapeutic profiles. Ultimately, a comprehensive understanding of pharmacodynamics is indispensable for advancing pharmacotherapy and improving patient outcomes in the realm of drug issues.
Title : Ectopically expressed olfactory receptors as an untapped family of drug targets and discovery of agonists and antagonists of OR51E1, an understudied G protein-coupled receptor
Vladlen Slepak, University of Miami Miller School of Medicine, United States
Title : Managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Analytical strategies for solid-state forms in drug development
Maria Cristina Gamberini, University of Modena e Reggio Emilia, Italy
Title : Understanding drug transport in plasma: The role of protein binding
Saad Tayyab, UCSI University, Malaysia
Title : Innovative development and delivery of biologics for chronic obstructive pulmonary disease
Yong Xiao Wang, Albany Medical College, United States
Title : Search for novel biomarkers and therapeutic targets for inflammatory disease
Madhav Bhatia, University of Otago, New Zealand
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through de-sign-inspired biotech- & biopharma-driven applications and upgraded business mar-keting to secure the human healthcare and biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : Design and evaluation of exo-itc: A bilayer fibrous system for controlled exosome delivery in dermatological applications
Luis Jesus Villarreal Gomez, FCITEC - Universidad AutĂłnoma de Baja California, Mexico
Title : Abuse-deterrent dosage form technique utilizing a fusion of innovative pharmaceuticals and ion exchange resin
Bhupendra Gopalbhai Prajapati, Parul University, India
Title : Macitentan/tadalafil combination– An additional value in pharmacotherapy of pulmonary arterial hypertension
Miroslav Radenkovic, University of Belgrade, Serbia