Drug Discovery and Screening

• In Vitro Models for Drug Screening

Drug discovery is a process where a new drug or medications are discovered and aims to identify a compound therapeutically useful in curing and treating disease. It includes a wide range of scientific divisions, including biology, chemistry, and pharmacology.

This process associates with the identification of candidates, synthesis, characterization, validation, optimization, screening, and assays for therapeutic efficacy.

The three major phases are:

• Formulation,
• Delivery,
• Packaging Development

Drug Development Phases includes:

• Phase 1: Discovery and Development.
• Phase 2: Preclinical Research.
• Phase 3: Clinical Research.
• Phase 4: FDA Review.
• Phase 5: FDA Post-Market Safety Monitoring.

Drug screening is a process where potential drugs are identified and optimized before the selection of a candidate drug to progress to clinical trials. It can involve screening large volumes of chemicals for a particular biological activity in high-throughput screening assays.

Drug screening mainly includes In-vivo and In-vivo models for drug screening