The creative process of discovering novel pharmaceuticals based on the understanding of a biological target is known as Drug Design, sometimes known as rational drug design or simply rational design. A protein, for example, is a frequent example of a biomolecule whose activity is activated or inhibited by the medicine, which benefits the patient therapeutically. Drug design, in its most basic sense, is creating compounds that interact with and bind to biomolecular targets that are complementary to one another in shape and charge. Computer modelling methods are commonly but not always used in drug design. Computer-aided drug design is another name for this kind of modelling. The term "Structure-Based Drug Design" refers to drug development that is based on an understanding of the biomolecular target's three-dimensional structure. In addition to small molecules, Biopharmaceuticals, such as peptides and therapeutic antibodies, are a growingly significant class of medications. Computational techniques have also been developed to enhance the affinities, selectivities, and stabilities of these protein-based treatments.
Title : Development of novel drug delivery pathways enabled by perillyl alcohol (NEO100), A monoterpene with multifaceted biomedical applications
Axel H Schonthal, University of Southern California, United States
Title : From marker to mechanism: Ligand discovery enables functional analysis of OR51E1, an ectopic olfactory receptor, in prostate cancer
Vladlen Slepak, University of Miami, United States
Title : Hepatotoxic botanicals-shadows of pearls
Consolato M Sergi, University of Alberta, Canada
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model based on design-inspired biotech- & biopharma-driven applications to secure the human healthcare and biosafety
Sergey Suchkov, N D Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : R&D consultancy at the medicines discovery catapult: De-risking drug discovery for innovators
Adriana Gambardella, Medicine Discovery Catapult, United Kingdom
Title : Biocompatible synthesis of non crystalline iron oxide nanoparticles with stable colloidal properties
Lan Wang, Paretor LLC, United States
Title : Precision diagnostics: Effectiveness of innovative imaging technologies for early detection of lung cancers
Huiqin Yang, ICON Clinical Research Ltd, United Kingdom
Title : Principles and standards for managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Design and characterization of gum arabic buccal films for protein drug delivery
Krisztian Pamlenyi, University of Szeged, Hungary
Title : Advancing EGFR-targeting macrocyclic peptide-drug conjugates to target KRAS-mutant solid tumors: Design, synthesis, and preclinical evaluations
Akash Panja, Ariel University, Israel