Drug Delivery Through BBB
  • Nanoparticle Delivery Across The BBB
  • Brain Penetration And Drug Delivery
  • The Blood-Brain Barrier In States Of Disease
  • Novel Approaches For Bbb Models

The Blood–brain barrier (BBB) is a highly selective semipermeable frontier of endothelial cells that prevents solutes in the circulating blood from non-selectively crossing into the extracellular fluid of the central nervous system where neurons reside.

BBB has been a great barrier to brain drug delivery. This is a healthy brain is a diffusion barrier essential for protecting normal brain function by impeding most compounds across the blood to the brain and only small molecules can cross the BBB.

A blood-brain barrier maintains homeostasis by obstructing toxic molecules from the circulation, but drugs are blocked at the same time. When the dose is increased to enhance the drug concentration in the central nervous system, then there will be side-effects on peripheral organs. In recent years, genetic therapeutic agents and small molecules have been used in various strategies to penetrate the BBB while minimizing the damage to systemic organs.

Committee Members
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Sergey Suchkov

Sergey Suchkov

Sechenov University and Moscow Engineering Physical Institute, Russian Federation
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Marino Nebuloni

Marino Nebuloni

Parma University, Italy
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Esmaiel Jabbari

Esmaiel Jabbari

University of South Carolina, United States
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Paul Millner

Paul Millner

University of Leeds, United Kingdom
PDDS 2021 Speakers
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Jan Versijpt

Jan Versijpt

University Hospital Brussels, Belgium
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Madhav Bhatia

Madhav Bhatia

University of Otago, New Zealand
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Stefanie Santos

Stefanie Santos

University Hospital Zurich, Switzerland
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Dmitry Ustyuzhanin

Dmitry Ustyuzhanin

National Medical Research Center of Cardiology, Russian Federation
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Anna Caprifico

Anna Caprifico

Kingston University, United Kingdom
Speaker at Pharmaceutics and Drug Delivery Systems 2021 - Annalisa Dalmoro

Annalisa Dalmoro

University of Salerno, Italy

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