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Drug Delivery Through BBB
  • Nanoparticle Delivery Across The BBB
  • Brain Penetration And Drug Delivery
  • The Blood-Brain Barrier In States Of Disease
  • Novel Approaches For Bbb Models

The Blood–brain barrier (BBB) is a highly selective semipermeable frontier of endothelial cells that prevents solutes in the circulating blood from non-selectively crossing into the extracellular fluid of the central nervous system where neurons reside.

BBB has been a great barrier to brain drug delivery. This is a healthy brain is a diffusion barrier essential for protecting normal brain function by impeding most compounds across the blood to the brain and only small molecules can cross the BBB.

A blood-brain barrier maintains homeostasis by obstructing toxic molecules from the circulation, but drugs are blocked at the same time. When the dose is increased to enhance the drug concentration in the central nervous system, then there will be side-effects on peripheral organs. In recent years, genetic therapeutic agents and small molecules have been used in various strategies to penetrate the BBB while minimizing the damage to systemic organs.

Committee Members
Speaker at Pharmaceutical Conference - Thomas J. Webster

Thomas J. Webster

Mansfield Bioincubator, United States
Speaker at Pharmaceutical Conference - Consolato M Sergi

Consolato M Sergi

University of Ottawa, Canada
Speaker at Drug Delivery Events - Sergey Suchkov

Sergey Suchkov

The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Speaker at Pharma Conferences - Saad Tayyab

Saad Tayyab

UCSI University, Malaysia
PDDS 2024 Speakers

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