Drug Delivery Through BBB
  • Nanoparticle Delivery Across The BBB
  • Brain Penetration And Drug Delivery
  • The Blood-Brain Barrier In States Of Disease
  • Novel Approaches For Bbb Models

The Blood–brain barrier (BBB) is a highly selective semipermeable frontier of endothelial cells that prevents solutes in the circulating blood from non-selectively crossing into the extracellular fluid of the central nervous system where neurons reside.

BBB has been a great barrier to brain drug delivery. This is a healthy brain is a diffusion barrier essential for protecting normal brain function by impeding most compounds across the blood to the brain and only small molecules can cross the BBB.

A blood-brain barrier maintains homeostasis by obstructing toxic molecules from the circulation, but drugs are blocked at the same time. When the dose is increased to enhance the drug concentration in the central nervous system, then there will be side-effects on peripheral organs. In recent years, genetic therapeutic agents and small molecules have been used in various strategies to penetrate the BBB while minimizing the damage to systemic organs.

PDDS 2022 Speakers
Speaker at Pharmaceutics and Drug Delivery Systems 2022 - Alena Korbut

Alena Korbut

IHS/Cherokee Nation, United States
Speaker at Pharmaceutics and Drug Delivery Systems 2022 - Victoria Demina

Victoria Demina

NEUWAY Pharma GmbH, Germany
Speaker at Pharmaceutics and Drug Delivery Systems 2022 - Samir Haddouchi

Samir Haddouchi

Sotax Pharma Services, France
Speaker at Pharmaceutics and Drug Delivery Systems 2022 - Miroslav Radenkovic

Miroslav Radenkovic

University of Belgrade, Serbia
Speaker at Pharmaceutics and Drug Delivery Systems 2022 - Mirjana B. Colovic

Mirjana B. Colovic

University of Belgrade, Serbia
Speaker at Pharmaceutics and Drug Delivery Systems 2022 - Madhav Bhatia

Madhav Bhatia

University of Otago, New Zealand

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