The goal of drug-excipient Compatibility studies is to detect, measure, and forecast possible interactions (physical or chemical), as well as the influence of these interactions on the manufacturability, quality, ad performance of the final therapeutic product. Excipients are chemicals that are included in dosage forms together with the active pharmaceutical ingredient (API). The majority of excipients have no direct pharmacological effect; however, they are useful for simplifying administration, regulating active component release, and stabilising API against degradation. However, improper excipients might cause accidental and/or unanticipated impacts on the chemical composition, stability, and bioavailability of the API, and hence their medicinal effectiveness and safety. In the development stage of all dosage forms, drug-excipient compatibility studies are a crucial step in finding interactions between prospective formulation excipients and the API.
Title : Principles and standards for managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : From marker to mechanism: Ligand discovery enables functional analysis of OR51E1, an ectopic olfactory receptor, in prostate cancer
Vladlen Slepak, University of Miami School of Medicine, United States
Title : Hydrogen sulfide in sepsis: From bench to bedside
Madhav Bhatia, University of Otago, New Zealand
Title : Tailored cellular environments to enable drug design
Lan Wang, Paretor LLC, United States
Title : Development of novel drug delivery pathways enabled by perillyl alcohol (NEO100), A monoterpene with multifaceted biomedical applications
Axel H Schonthal, University of Southern California, United States
Title : A NAMs-compatible mechanopharmacological model of drug penetration in the urinary bladder
Kunal Sharma, Swisss Federal Institute of Technology Lausanne, Switzerland
Title : Application of quality by design for pulmonary liposomes: Preliminary study to nano in-microparticle
Lucas Amaral Machado, University of Sao Paulo State – UNESP, Brazil
Title : Integrated Raman, SERS and computational approaches for the study of bioactive molecules in pharmaceutical chemistry
Maria Cristina Gamberini, University of Modena and Reggio Emilia, Italy
Title : The impact of metal-decorated polymeric nanodots on proton relaxivity
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Hepatotoxic botanicals-shadows of pearls
Consolato M Sergi, University of Alberta, Canada