Chronopharmacology, a branch of pharmacology, investigates the influence of drug administration timing on the body's circadian rhythms. The suprachiasmatic nucleus regulates the body's internal clock, impacting the expression of drug-metabolizing enzymes and influencing pharmacokinetics. This understanding enables the optimization of drug timing, enhancing therapeutic benefits while minimizing side effects. Applications extend to cardiovascular, cancer, and neurological treatments, recognizing the profound impact of timing on outcomes. Moreover, studies have revealed that the efficacy and toxicity of certain medications vary significantly based on the time of administration, emphasizing the importance of aligning drug delivery with the patient's circadian rhythm. Chronotherapy, part of chronopharmacology, tailors drug administration to individual circadian rhythms, advancing personalized medicine. Ongoing research explores deeper connections between circadian rhythms and drug responses. Integrating chronopharmacology into clinical practice requires addressing challenges of patient variability and practical implementation of time-specific drug regimens.
Title : Medical liver biopsy: Toward a personalized approach
Consolato M Sergi, Universities of Alberta and Ottawa, Canada
Title : Macitentan/tadalafil combination– An additional value in pharmacotherapy of pulmonary arterial hypertension
Miroslav Radenkovic, University of Belgrade, Serbia
Title : Ectopically expressed olfactory receptors as an untapped family of drug targets and discovery of agonists and antagonists of OR51E1, an understudied G protein-coupled receptor
Vladlen Slepak, University of Miami Miller School of Medicine, United States
Title : Mathematical modeling the disc diffusion test: Antibacterial activity of copper-doped SnO2
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Emerging formulation and delivery applications of Vitamin E TPGS
Andreas M Papas, Antares Health Products, United States
Title : The promise of nanotechnology in personalized & precision medicine: Drug discovery & development being partnered with nanotechnologies via the revolution at the nanoscale
Sergey Suchkov, The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through design-inspired biotech- & biopharma-driven applications and upgraded business marketing to secure the human healthcare and biosafety
Sergey Suchkov, The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Title : Design and evaluation of exo-itc: A bilayer fibrous system for controlled exosome delivery in dermatological applications
Luis Jesus Villarreal Gomez, FCITEC - Universidad AutĂłnoma de Baja California, Mexico
Title : Antibody-proteases as translational tools of the next-step generation to be applied for biopharmacy-related and precision medical practice
Sergey Suchkov, The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Title : Understanding drug transport in plasma: The role of protein binding
Saad Tayyab, UCSI University, Malaysia