Chronopharmacology, a branch of pharmacology, investigates the influence of drug administration timing on the body's circadian rhythms. The suprachiasmatic nucleus regulates the body's internal clock, impacting the expression of drug-metabolizing enzymes and influencing pharmacokinetics. This understanding enables the optimization of drug timing, enhancing therapeutic benefits while minimizing side effects. Applications extend to cardiovascular, cancer, and neurological treatments, recognizing the profound impact of timing on outcomes. Moreover, studies have revealed that the efficacy and toxicity of certain medications vary significantly based on the time of administration, emphasizing the importance of aligning drug delivery with the patient's circadian rhythm. Chronotherapy, part of chronopharmacology, tailors drug administration to individual circadian rhythms, advancing personalized medicine. Ongoing research explores deeper connections between circadian rhythms and drug responses. Integrating chronopharmacology into clinical practice requires addressing challenges of patient variability and practical implementation of time-specific drug regimens.
Title : Ectopically expressed olfactory receptors as an untapped family of drug targets and discovery of agonists and antagonists of OR51E1, an understudied G protein-coupled receptor
Vladlen Slepak, University of Miami Miller School of Medicine, United States
Title : Managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Analytical strategies for solid-state forms in drug development
Maria Cristina Gamberini, University of Modena e Reggio Emilia, Italy
Title : Understanding drug transport in plasma: The role of protein binding
Saad Tayyab, UCSI University, Malaysia
Title : Innovative development and delivery of biologics for chronic obstructive pulmonary disease
Yong Xiao Wang, Albany Medical College, United States
Title : Search for novel biomarkers and therapeutic targets for inflammatory disease
Madhav Bhatia, University of Otago, New Zealand
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through de-sign-inspired biotech- & biopharma-driven applications and upgraded business mar-keting to secure the human healthcare and biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : Design and evaluation of exo-itc: A bilayer fibrous system for controlled exosome delivery in dermatological applications
Luis Jesus Villarreal Gomez, FCITEC - Universidad AutĂłnoma de Baja California, Mexico
Title : Abuse-deterrent dosage form technique utilizing a fusion of innovative pharmaceuticals and ion exchange resin
Bhupendra Gopalbhai Prajapati, Parul University, India
Title : Macitentan/tadalafil combination– An additional value in pharmacotherapy of pulmonary arterial hypertension
Miroslav Radenkovic, University of Belgrade, Serbia