Bioactive materials include bio ceramics like hydroxyapatite and bioactive glass, as well as synthetic biodegradable polymers like PLA/PGA copolymers and natural biopolymer-based biometrics like collagen, chitosan, and hyaluronic acid. Bioactive materials have been employed in clinical applications by several medical specialities, including dermatology, cardiology, urology, cancer, dental materials, and wound care, as means of delivering bioactive substances. The difficulties in achieving a controlled release profile due to the materials' structures, the complexity of regulatory issues, the selection of drugs, the distinction between in vitro and in vivo conditions, and the evaluation of device stability are just a few limitations for bioactive materials used in drug delivery. Future developments in this area will concentrate on developing delivery systems that make use of structurally distinct bioactive compounds.
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