Bioavailability, crucial in pharmacology and nutrition, determines how efficiently a substance enters the bloodstream and reaches its target. In pharmaceuticals, it measures the portion of a dose that achieves systemic circulation, overcoming challenges like liver metabolism and gastrointestinal obstacles. Optimizing bioavailability is essential in drug formulation to ensure intended therapeutic effects. In nutrition, bioavailability governs the body's efficiency in absorbing essential nutrients from ingested food, impacted by factors like food processing and individual variations, influencing overall health. Understanding bioavailability involves exploring absorption mechanisms, bodily fluid transport, and metabolic interplay. Researchers enhance it through innovative delivery systems, considering substance solubility and tailoring formulations for optimal absorption rates.
In essence, whether in pharmaceuticals or nutrition, bioavailability is a dynamic and intricate parameter crucial for maximizing therapeutic impact or nutritional benefit. Its mastery reflects the delicate dance between scientific understanding, precise formulation, and the complex physiological intricacies of the human body.
Title : Ectopically expressed olfactory receptors as an untapped family of drug targets and discovery of agonists and antagonists of OR51E1, an understudied G protein-coupled receptor
Vladlen Slepak, University of Miami Miller School of Medicine, United States
Title : Managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Analytical strategies for solid-state forms in drug development
Maria Cristina Gamberini, University of Modena e Reggio Emilia, Italy
Title : Understanding drug transport in plasma: The role of protein binding
Saad Tayyab, UCSI University, Malaysia
Title : Innovative development and delivery of biologics for chronic obstructive pulmonary disease
Yong Xiao Wang, Albany Medical College, United States
Title : Search for novel biomarkers and therapeutic targets for inflammatory disease
Madhav Bhatia, University of Otago, New Zealand
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through de-sign-inspired biotech- & biopharma-driven applications and upgraded business mar-keting to secure the human healthcare and biosafety
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
Title : Design and evaluation of exo-itc: A bilayer fibrous system for controlled exosome delivery in dermatological applications
Luis Jesus Villarreal Gomez, FCITEC - Universidad AutĂłnoma de Baja California, Mexico
Title : Abuse-deterrent dosage form technique utilizing a fusion of innovative pharmaceuticals and ion exchange resin
Bhupendra Gopalbhai Prajapati, Parul University, India
Title : Macitentan/tadalafil combination– An additional value in pharmacotherapy of pulmonary arterial hypertension
Miroslav Radenkovic, University of Belgrade, Serbia