Bioavailability, crucial in pharmacology and nutrition, determines how efficiently a substance enters the bloodstream and reaches its target. In pharmaceuticals, it measures the portion of a dose that achieves systemic circulation, overcoming challenges like liver metabolism and gastrointestinal obstacles. Optimizing bioavailability is essential in drug formulation to ensure intended therapeutic effects. In nutrition, bioavailability governs the body's efficiency in absorbing essential nutrients from ingested food, impacted by factors like food processing and individual variations, influencing overall health. Understanding bioavailability involves exploring absorption mechanisms, bodily fluid transport, and metabolic interplay. Researchers enhance it through innovative delivery systems, considering substance solubility and tailoring formulations for optimal absorption rates.
In essence, whether in pharmaceuticals or nutrition, bioavailability is a dynamic and intricate parameter crucial for maximizing therapeutic impact or nutritional benefit. Its mastery reflects the delicate dance between scientific understanding, precise formulation, and the complex physiological intricacies of the human body.
Title : Medical liver biopsy: Toward a personalized approach
Consolato M Sergi, Universities of Alberta and Ottawa, Canada
Title : Macitentan/tadalafil combination– An additional value in pharmacotherapy of pulmonary arterial hypertension
Miroslav Radenkovic, University of Belgrade, Serbia
Title : Ectopically expressed olfactory receptors as an untapped family of drug targets and discovery of agonists and antagonists of OR51E1, an understudied G protein-coupled receptor
Vladlen Slepak, University of Miami Miller School of Medicine, United States
Title : Mathematical modeling the disc diffusion test: Antibacterial activity of copper-doped SnO2
Paulo Cesar De Morais, Catholic University of Brasilia, Brazil
Title : Emerging formulation and delivery applications of Vitamin E TPGS
Andreas M Papas, Antares Health Products, United States
Title : The promise of nanotechnology in personalized & precision medicine: Drug discovery & development being partnered with nanotechnologies via the revolution at the nanoscale
Sergey Suchkov, The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through design-inspired biotech- & biopharma-driven applications and upgraded business marketing to secure the human healthcare and biosafety
Sergey Suchkov, The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Title : Design and evaluation of exo-itc: A bilayer fibrous system for controlled exosome delivery in dermatological applications
Luis Jesus Villarreal Gomez, FCITEC - Universidad AutĂłnoma de Baja California, Mexico
Title : Antibody-proteases as translational tools of the next-step generation to be applied for biopharmacy-related and precision medical practice
Sergey Suchkov, The Russian University of Medicine and Russian Academy of Natural Science-Moscow, Russian Federation
Title : Understanding drug transport in plasma: The role of protein binding
Saad Tayyab, UCSI University, Malaysia