The full PDDS 2026 scientific program across 3 days — keynotes, oral presentations, and posters. Talks are ordered by program prominence within each day.
Day 1
- Keynote · Virtual
Non-crystalline stabilization of iron-oxide nanoparticles enables a versatile platform for carrier-dependent and carrier-free drug delivery
Lan Wang · Paretor LLC, United States
We investigated alternative routes for tuning nanoparticle drug-delivery behavior by deliberately disrupting spinel lattice formation during iron-oxide: magnesium synthesis. Under constrained, automation-compatible…
- Keynote · Virtual
Azobenzene-enriched PEG-PLGA micelles as a light-responsive drug delivery platform: Effect of light on biological activity
Mila Radan · University of Split, Croatia (Hrvatska)
Azobenzene derivatives have the potential to enable light-induced modulation of biological activity. In this study, azobenzene-enriched PEG-PLGA micelles were developed as a delivery system for a selected anticancer…
- Oral · In-Person
Tailored cellular environments to enable drug design
Lan Wang · Paretor LLC, United States
Over the past 50 years, drug delivery has evolved from localized injection to basic pharmacokinetic optimization to targeted intracellular delivery of therapeutics. While these advancements have been critical for…
- Oral · In-Person
Application of quality by design for pulmonary liposomes: Preliminary study to nano in-microparticle
Lucas Amaral Machado · University of Sao Paulo State – UNESP, Brazil
Introduction: Pulmonary surfactants in liposomes production became relevant components due to their compatibility with the pulmonary environment. However, the understanding of critical process parameters (CPP) needs to…
- Oral · In-Person
Personalized and Precision Medicine (PPM) as a unique healthcare model based on design-inspired biotech- & biopharma-driven applications to secure the human healthcare and biosafety
Sergey Suchkov · N D Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, InMedStar and Biona, Russian Federation
Despite breakthroughs in research that have led to an increased understanding of PPM-based human disease, the translation of discoveries into therapies for patients has not kept pace with medical need. Modern drugs are…
- Oral
An injectable CarboCell depot technology for local, sustained dual-antibiotic delivery in bone infections
Niranjan G Kotla · Technical University of Denmark (DTU), Denmark
Chronic bone infections remain difficult to treat, as systemic antibiotic therapy often fails to achieve sufficient local drug concentrations in poorly vascularized, infected bone while simultaneously exposing patients…
- Oral
Novel fabrication of adaptive transdermal technologies for drug delivery
Zeeshan Ahmad · University of Manchester, United Kingdom
Transdermal drug delivery systems (and technologies) have undergone substantial transformations over the last decade due to advances in 3D Printing, Micromoulding and other novel processing technologies. This…
- Oral
Rational optimization of antibody–cyanine bioconjugates for targeted theranostic drug delivery and photo/sono activation
Amartya Sanyal · Ariel University, Israel
Photodynamic therapy (PDT) is a well-established treatment modality; however, its clinical translation is limited by poor light penetration in deep tissues. Sonodynamic therapy (SDT), which utilizes ultrasound as an…
- Oral
Design and characterization of gum arabic buccal films for protein drug delivery
Krisztian Pamlenyi · University of Szeged, Hungary
Oral mucoadhesive drug delivery systems, particularly buccal films, have gained increasing attention as promising alternatives to conventional dosage forms. These flexible systems adhere to the oral mucosa for extended…
- Oral
Biocompatible synthesis of non crystalline iron oxide nanoparticles with stable colloidal properties
Lan Wang · Paretor LLC, United States
Biocompatible iron oxide nanoparticles (IONPs) are widely used in targeted and responsive delivery, yet conventional formulations adopt crystalline spinel phases that generate magnetic interactions and aggregation…
- Oral
Design and optimization of a nanotechnological platform for future delivery of Sarcomphalus joazeiro (Mart.) extract in dental bleaching
Lucas Amaral Machado · University of Sao Paulo State – UNESP, Brazil
Although effective in removing stains from teeth, peroxides can trigger severe side effects, such as gum inflammation and dental hypersensitivity, due to free radical penetration into dentinal tubules. In this scenario…
- Oral
Antibody proteases as translational tools of the next step generation to be applied for biopharmacy related and precision medical practice
Sergey Suchkov · N D Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, InMedStar and Biona, Russian Federation
High impact of Ab-proteases is valuable to monitor both clinical and subclinical courses of chronic autoimmune inflammation to predict stepwise transformations of the course, starting from the pre-illness and to…
- Oral · In-Person
Structure-based discovery of kinetic stabilizers for transthyretin amyloidosis
Salvador Ventura · Universitat Autònoma de Barcelona, Spain
Transthyretin amyloidosis (ATTR) is a group of fatal protein misfolding disorders caused by the dissociation and aggregation of the transthyretin (TTR) tetramer. Tetramer destabilization, driven by aging or pathogenic…
Day 2
- Keynote
From marker to mechanism: Ligand discovery enables functional analysis of OR51E1, an ectopic olfactory receptor, in prostate cancer
Vladlen Slepak · University of Miami School of Medicine, United States
OR51E1 is a G protein-coupled receptor that belongs to the family of olfactory receptors, but is found in a few tissues outside the nasal epithelium. It widely reported as a prostate cancer–associated marker, yet its…
- Keynote
Principles and standards for managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel · University of Regensburg, Germany
For realizing pervasive and ubiquitous health and social care services, health and social care system have to undergo an organizational, methodological and technological transformation towards personalized…
- Keynote
Development of novel drug delivery pathways enabled by perillyl alcohol (NEO100), A monoterpene with multifaceted biomedical applications
Axel H Schonthal · University of Southern California, United States
Perillyl alcohol is a naturally occurring monoterpene related to limonene. We have synthesized a clinical-grade version, called NEO100 (NeOnc Technologies, Inc., Los Angeles, California), which has revealed a variety of…
- Keynote
Integrated Raman, SERS and computational approaches for the study of bioactive molecules in pharmaceutical chemistry
Maria Cristina Gamberini · University of Modena and Reggio Emilia, Italy
Raman and surface-enhanced Raman scattering spectroscopy have become valuable tools in pharmaceutical chemistry because they combine molecular selectivity, limited sample preparation and the possibility of analysing…
- Keynote
Hepatotoxic botanicals-shadows of pearls
Consolato M Sergi · University of Alberta, Canada
Objective: The utilization of herbal medicines has risen globally. Recently, the possible adverse effects of certain herbs have been observed, particularly concerning hepatotoxicity associated with the consumption of…
- Keynote
The impact of metal-decorated polymeric nanodots on proton relaxivity
Paulo Cesar De Morais · Catholic University of Brasilia, Brazil
The present talk will discuss experimental data regarding successful fabrication of a novel Cu 2+ -complex of nitrogen-rich polymer nanodots, with a mean diameter of about 20 nm extracted from transmission electron…
- Keynote
Precision diagnostics: Effectiveness of innovative imaging technologies for early detection of lung cancers
Huiqin Yang · ICON Clinical Research Ltd, United Kingdom
Diagnosis of lung cancer often occurs in its later disease stage. The prognosis for long term survival for patients with lung cancer is very poor. Early detection of lung cancers can be associated with a reduction in…
- Keynote
Biocompatibility and subcutaneous host response to silk fibroin–chitosan composite plugs: Progress toward biodegradable implant materials
Luis Jesus Villarreal Gomez · Universidad Autónoma de Baja California, Mexico
Silk fibroin (SF) and chitosan (CS) are promising biopolymers for biodegradable scaffolds in regenerative therapies. Here, we produced SF/CS composite plugs at 70:30 and 60:40 ratios and compared them to single-polymer…
- Keynote · In-Person
Development and characterization of dual-functional nanofibrous dressing system for burn wound management
Adrienn Nochta Kazsoki · Semmelweis University, Hungary
Introduction: Burn wound management remains a considerable clinical challenge, particularly in cases where rapid tissue regeneration, effective infection control, and the prevention of excessive scar formation are…
- Keynote · In-Person
Diabetes risk stratification using self-reported health indicators: A machine learning and explainability approach
Tanuja Tummala · Harrisburg University of Science and Technology, United States
This study presents a machine learning approach to classify diabetes status using the CDC BRFSS 2015 dataset, which includes over 250,000 self-reported health records across 22 variables. The goal was to develop a…
- Keynote · In-Person
Cognitivevoice: Novel machine learning model leveraging acoustic features to predict future cognitive decline in Parkinson’s Disease
Aadya Daga · Hamilton High School, United States
Parkinson’s Disease (PD) is the second most common neurodegenerative disorder in the world. While it primarily hinders motor functions, PD also causes cognitive dysfunctions which can progress to severe conditions like…
- Oral
R&D consultancy at the medicines discovery catapult: De-risking drug discovery for innovators
Adriana Gambardella · Medicine Discovery Catapult, United Kingdom
The Medicines Discovery Catapult (MDC) is a UK-based national life sciences service, headquartered in Alderley Park, supporting innovators across the full drug discovery and early development pathway through R&D…
- Poster
Characterization, antibacterial, and cytotoxic activities of silver nanoparticles using the whole biofilm layer as a macromolecule in biosynthesis
Aghapy Yermans Yakoup · Zewail City for Science and Technology, Egypt
Recently, multi-drug resistant (MDR) bacteria are responsible for a large number of infectious diseases that can be life-threatening. Globally, new approaches are targeted to solve this essential issue. This study aims…
- Poster
Polyphenols as pharmaceutical active ingredients: Current challenges in bioavailability and novel drug delivery
Roman Lysiuk · Danylo Halytsky Lviv National Medical University, Ukraine
Plant polyphenols comprise several major classes, including flavonoids, phenolic acids, stilbenes, lignans, and related compounds. Beyond their classical role as antioxidants, they act as pleiotropic modulators of…
- Poster
GC-MS/FID analysis of tea tree oil and development of its nanostructured lipid carriers
Cemre Irem Ayguler · Acıbadem Mehmet Ali Aydınlar University, Turkey
Tea tree oil (TTO), derived from Melaleuca alternifolia, exhibits antimicrobial, antifungal, antiviral, and anti-inflammatory properties. However, its effectiveness is limited due to its susceptibility to oxidation…
- Poster
QSAR analysis in drug design: A retrospective, current state, and case studies of mapping structure–activity landscapes of thiazolopyridine-based APIs
Olena Klenina · Danylo Halytsky Lviv National Medical University, Ukraine
The development of modern therapeutics relies heavily on Quantitative Structure-Activity Relationship (QSAR) methodologies to guide rational drug design, optimize lead compounds, and minimize empirical trial-and-error.…
- Poster
In silico investigation of thiazolo[4,5-b]pyridine derivatives as potential anti-inflammatory and antioxidant agents
Olena Klenina · Danylo Halytsky Lviv National Medical University, Ukraine
This presentation focuses on the design, evaluation, and computational analysis of thiazolo[4,5-b]pyridine-2-one derivatives, with particular emphasis on in silico approaches used to predict their biological activity.…
- Poster
Infant exposure to cannabinoids via the mother’s milk
Anna W Sobanska · Medical University of Lodz, Poland
Cannabinoids are the primary active compounds in Cannabis sativa, which has been used for over 4000 years as a recreational drug. The main psychoactive constituent of hemp is Δ9-tetrahydrocannabinol (Δ9-THC). In plants…
- Poster
Evaluation of surface-charged donepezil-loaded liposomes for intranasal nose-to-brain drug delivery
Elika Valehi · University of Szeged, Hungary
Intranasal drug administration has gained considerable attention as a non-invasive approach for delivering therapeutic agents directly to the central nervous system (CNS). This route provides the potential to bypass the…
- Poster
Platelet-activating factor-receptor pathway mediates solar radiation-induced extracellular vesicle release in human keratinocytes
Ravi P Sahu · Wright State University, United States
Solar ultraviolet (UV) radiation is a major environmental toxicant that contributes to inflammation, immunosuppression, and carcinogenesis. Previous studies suggest that UVB-induced oxidative stress generates oxidized…
- Poster
Artificial Intelligence and digital twins in drug product development: Shaping the future of regulatory science
Bhasker Sambar · Alvogen Inc, United States
Background & Rationale: Regulatory agencies including the FDA, EMA, and ICH are increasingly recognizing the value of Artificial Intelligence (AI) and Digital Twin (DT) technologies in pharmaceutical development. FDA's…
Day 3
- Keynote
Hydrogen sulfide in sepsis: From bench to bedside
Madhav Bhatia · University of Otago, New Zealand
Sepsis is a major health problem worldwide. It is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis-related deaths represent 19·7% of deaths from all causes…
- Keynote
From nanoparticles to microneedles: Emerging strategies in skin cancer treatment
Anil Pareek · Anand Pharmacy College, India
The incidence rate of skin cancer is very high around the globe, making melanoma and non-melanoma skin cancer serious concerns to the community at large. Current methods used for managing these cancers are limited by…
- Keynote
From in silico docking to in vivo relevance: Predicting drug binding to ligand-bound human serum albumin
Saad Tayyab · UCSI University, Malaysia
Binding of drugs to plasma proteins plays a critical role in determining pharmacokinetics, bioavailability, and therapeutic efficacy. Among plasma proteins, Human Serum Albumin is the primary carrier responsible for…
- Keynote
Combinational in silico methods-based screening and selection of druggable targets in certain immune, non-immune and stromal cells in TNBC TME - Lessons for delivery of natural molecules with differentiation potential
Suresh P.K · VIT University, India
Based on existing diagnostic data, Breast Cancer (BC) stands second globally and is also a significant contributor to cancer-related deaths in women 1 in several countries including India, necessitating research…
- Poster
A NAMs-compatible mechanopharmacological model of drug penetration in the urinary bladder
Kunal Sharma · Swisss Federal Institute of Technology Lausanne, Switzerland
Conventional antibiotic efficacy metrics fail to capture the mechanopharmacology of bladder infections, where pathogens persist within protected intracellular and subepithelial reservoirs that drive chronic disease. The…
- Poster
From design to activity: Linker flexibility in 3-spiro-2-oxindoline VEGFR-2 inhibitors
Tarek Aboul Fadl · Assiut University, Egypt
A series of novel 3-spiro-2-oxindoline derivatives incorporating an aromatic hydrazide linker were rationally designed and synthesized as potential VEGFR-2 inhibitors. This work specifically aimed to evaluate the…
- Poster
Development of a next-generation hepatocyte-targeted nucleic acid delivery platform evading LDLR dependence and PEG-related immunogenicity
Helen Cho · Samyang Biopharm Corporation, Korea, Republic of
An effective nucleic acid therapeutic delivery system must ensure consistent performance across both healthy and diseased liver conditions, support repeat dosing without inducing toxicity, and minimize immunogenic…
- Poster
Exploring classical ayurvedic drugs in hypertension
Prashant Sakharam Bhokardankar · Datta Meghe Ayurvedic Medical College Hospital and Research Centre, India
Hypertension is a lifestyle disorder. Mostly the disorder is asymptomatic until it gets diagnosed. Hypertension for a longer duration if gets uncontrolled can cause the problems to the eye, kidney blood vessels, and…
- Poster
Formulation, optimization, and in vitro characterization of chitosan–alginate polyelectrolyte complex microbeads incorporated into a natural hydrophilic matrix for extended oral delivery of an antihypertensive drug
Rama Rao Nadendla · Chalapathi Institute of Pharmaceutical Sciences, India
Hypertension is a major chronic cardiovascular disorder requiring prolonged pharmacotherapy and consistent maintenance of therapeutic plasma concentrations to achieve optimal clinical outcomes. Conventional…
- Poster
Development of liquid formulations of plasma proteins
Bhupendra G Prajapati · Parul University, India
Formulating plasma proteins as liquid dosage forms is challenging due to limited excipients and risks of physical and chemical instability, including aggregation and loss of efficacy. Strategies such as DoE, QbD, and…
- Poster
Pharmaceutical contaminants in the environment: Risk assessment challenges and remediation approaches
Neha Agarwal · Navyug Kanya Mahavidyalaya, India
Pharmaceuticals are essential for maintaining human health and have become an indispensable part of modern life. However, their widespread and often uncontrolled use has led to growing concerns about environmental…
- Poster
Structure-based design and smart formulation of stimuli-responsive nanocarriers: Bridging computational docking with advanced drug delivery for targeted therapeutics
Pradeepa Prasad · The Oxford College of Pharmacy, India
Oxazolone derivatives have gained significant attention due to their wide spectrum of biological activities, particularly anticancer potential. Breast cancer remains a leading cause of mortality among women…
- Poster
Cannabis therapeutic formulations: SWOT analysis
Parikshit R Shirode · Parul University, India
Background: Cannabis has been employed medicinally across nearly all ancient civilizations, with references in the Vedas and classical Ayurvedic texts. Traditionally, it was advocated for acute and chronic pain…
- Poster
Formulation and development of herbal in-situ sustained release otic gel for the treatment of otitis media using Eclipta alba
Dev Soni · Shree Swaminarayan Sanskar Pharmacy College, India
Otitis media remains one of the most common ear infections in young children, and conventional otic formulations often suffer from short residence time and rapid drainage from the ear canal, limiting therapeutic…
- Poster
Development of arteether nanoemulsion for improved oral bioavailability and antimalarial efficacy against Plasmodium yoelii nigeriensis
Priyanka Chaturvedi · Jai Narain College of Pharmacy, JNCTPU, India
Background: Arteether (ART) is a potent antimalarial drug, but its clinical utility is limited due to low aqueous solubility and poor oral bioavailability. This study aimed to develop an ART-loaded nanoemulsion (ART-NE)…
- Poster
Fabrication, characterization, and evaluation of pyrazinamide-loaded immediate-release tablets via fused deposition modeling 3D printing for personalized tuberculosis treatment
Shubham Singh · Maharaja Ranjit Singh Punjab Technical University, India
Purpose: Paediatric tuberculosis (TB) treatment is challenged by the need for age-appropriate dosage forms, flexible dose adjustment, and improved patient adherence. Three-dimensional (3D) printing has become an…
- Poster
Nanotechnology in pharmaceutics and drug delivery systems: A medicinal mathematics perspective
Vishwa Mehul Patel · Shri Swaminarayan Institute, India
Nanotechnology has emerged as a transformative approach in pharmaceutics and drug delivery systems, enabling precise targeting, controlled drug release, and improved bioavailability of therapeutic agents. This…
Present your research at PDDS 2027
Abstract submissions for the 2027 program are open · September 13–15, 2027 · Olympia Hotel, Events & Spa, Valencia, Spain.
Join the PDDS 2027 delegation
Valencia · September 13–15, 2027 · Hybrid · in-person & virtual
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