Title : Cannabis therapeutic formulations: SWOT analysis
Abstract:
Background: Cannabis has been employed medicinally across nearly all ancient civilizations, with references in the Vedas and classical Ayurvedic texts. Traditionally, it was advocated for acute and chronic pain management, insomnia, and anxiety. However, during the rise of modern pharmaceuticals such as steroids and synthetic analgesics, cannabis was marginalized. Today, global interest is resurging, with renewed hope for cannabis-based therapeutics. The global cannabis market is projected to grow up to USD 125.76 billion by 2030.
Objective: This paper aims to critically evaluate cannabis therapeutic formulations through a SWOT (Strengths, Weaknesses, Opportunities, Threats) framework, bridging traditional Ayurvedic wisdom
with modern pharmaceutical innovation. Methods: A review of classical Ayurvedic formulations—including tablets, decoctions, medicated oils, and ghee—was undertaken alongside modern extract-based products such alongside modern extract-based products such as full-spectrum and targeted cannabinoid gels, sprays, oils, and transdermal patches. Routes of administration analyzed include oral, nasal, transdermal, topical, and sublingual. Regulatory perspectives and market trends were also considered.
Results/Discussion:
- Strengths: Historical validation, broad therapeutic potential, and diverse formulation options.
- Weaknesses: Regulatory restrictions, social stigma, and variability in phytoconstituent standardization.
- Opportunities: Integration of traditional and modern delivery systems, expanding global acceptance, and potential for evidence-based nutraceuticals.
- Threats: Policy uncertainties, risk of misuse, and competition with established pharmaceuticals.
Conclusion: Cannabis therapeutic formulations represent a unique convergence of ancient knowledge and modern science. A structured SWOT analysis highlights the need for rigorous validation, strategic regulation, and innovative product development to ensure safe and effective integration into contemporary healthcare
