3rd Edition of Global Conference on
Pharmaceutics and Drug Delivery Systems
- June 24-26, 2019
- Paris, France
Extensive use of the natural materials in the field of drug delivery have been owed to their ready availability, cost-effectiveness, eco-friendliness, capability of undergoing multitude of chemical modifications, potential degradability and compatibility due to their natural origin. Makapuno coconut (Cocos nucifera Linn.) yields a high value byproduct called galactomannan which offers many commercial possibilities for the food, pharmaceutical and other industries. Galactomannan, a water-soluble gum, possesses a complex, branched polymeric structure because of which they exhibit high cohesive and adhesive properties such properties used in pharmaceutical preparation. The main objective of the study is to characterize the galactomannan synthesized from Cocos nucifera cv. Makapuno. The average percentage yield of galactomannan isolated from Cocos nucifera cv. Makapuno is 12.53%. The isolated galactomannan is creamy white, with distinct odor and irregular shape. The pH value of 4.72, moisture content of 1.60% and loss on drying of 2.15% and results of microbial test and IR spectrum are acceptable if compared to commercially available galactomannan (Guar Galactomannan). Makapuno Gum is soluble in water, partly soluble in 70% alcohol, and insoluble in 90% alcohol, methanol, acetonitrile and glycerin. The isolated Makapuno gum is practically comparable to commercially available galactomannan (Guar Galactomannan) in terms of pH, moisture content, loss on drying and microbial count, with some commercially available galactomannans and can be used for industrial applications to make higher-value products.