Title : Role of natural polymers in drug delivery system
Abstract:
In recent years, various types of natural polymers have gained prominence in drug delivery systems due to their biocompatibility, biodegradability, and ease of modification. Recent research has further enhanced the capabilities of these polymers, expanding their functions in drug delivery. This presentation will focus on the role of natural polymers in modifying drug release patterns, particularly the dual release pattern (immediate and sustained release) achieved through the natural composition of a single polymer. We have explored the recent discovery of banana starch, which demonstrates a promising combination of amylose and amylopectin, approximately in a 26-28:72-74 ratios. Amylose is a straight-chain polymer of D-glucose linked by 1-4 glycosidic bonds, while amylopectin is a branched-chain polymer of D-glucose linked by α-1,4 glycosidic bonds and α-1,6 glycosidic bonds. These structural differences impart unique drug release properties: amylose facilitates immediate release, while amylopectin provides sustained release. This dual release capability makes banana starch an intriguing candidate for drug delivery applications. Furthermore, banana starch is likely not the only natural polymer with such advantageous compositions. The presentation will highlight the need for continued research to identify other natural polymers that exhibit similar or superior functionalities for drug delivery. By delving into these topics, we aim to shed light on the potential of natural polymers to revolutionize drug delivery systems, enhancing therapeutic efficacy and patient compliance through innovative release mechanisms.
Audience Take Away Notes:
- Designing Advanced Drug Delivery Systems: By understanding the properties of natural polymers like banana starch, the audience can design drug delivery systems that utilize dual release patterns. This can help in creating formulations that release drugs both immediately and over a sustained period, improving therapeutic outcomes
- Developing New Formulations: The insights into the structural differences between amylose and amylopectin and their impact on drug release can guide the development of new drug formulations. This knowledge can be applied to tailor the release profiles of various drugs to meet specific medical needs
- Innovating in Pharmaceutical Research: Researchers and scientists can use the information to explore and identify other natural polymers with similar beneficial properties. This can lead to the discovery of new materials that can be used in innovative drug delivery systems
- Enhancing Product Performance: Pharmaceutical companies can apply the principles learned to enhance the performance of their existing products. By incorporating natural polymers that provide controlled release, they can improve patient compliance and satisfaction
- Advancing Environmental Sustainability: By adopting biodegradable and biocompatible natural polymers, the audience can contribute to the development of eco-friendly pharmaceutical products. This aligns with global sustainability goals and can improve the environmental impact of drug delivery systems
- Strengthening Competitive Edge: Knowledge of the latest advancements in natural polymer applications will provide a competitive advantage. Professionals can leverage this information to stay ahead in the industry by offering cutting-edge solutions that meet the evolving needs of patients and healthcare providers
- Collaborating Across Disciplines: The multidisciplinary nature of drug delivery research can foster collaboration between chemists, biologists, materials scientists, and pharmaceutical professionals. The shared understanding of natural polymers can enhance cross-functional projects and innovations
- Informing Clinical Practice: Clinicians can use the insights to better understand the pharmacokinetics of new drug formulations, leading to more informed prescribing practices and improved patient care
- Enhance Knowledge of Drug Delivery Mechanisms: Understanding the dual release pattern (immediate and sustained release) of natural polymers like banana starch will enable professionals to design more effective drug delivery systems
- Inspire Innovative Solutions
- Improve Product Development
- Encourage Research and Development
- This research on natural polymers in drug delivery systems is highly valuable for other faculty and can be used to expand their research and teaching in several ways: Interdisciplinary Collaboration, New Research Projects, Grant Proposals, Publications and Conferences
- This research on natural polymers in drug delivery systems provides several practical solutions that can simplify and make a designer's job more efficient:
1. Enhanced Drug Formulation Simplified Development Process Versatile Applications
2. Improved Biocompatibility: Reduced Adverse Reactions Regulatory Advantages
3. Sustainable Design: Eco-Friendly Solutions Market Differentiation
4. Cost-Effective Production Reduced Costs Scalability
5. Functional Flexibility Customization Multi-Functionality
6. Streamlined Research and Development Focused Research Collaboration Opportunities
7. User-Friendly Products - This research on natural polymers in drug delivery systems will improve the accuracy of designs and provide new information to assist in solving design problems in several key ways:
1. Improved Accuracy of Designs
2. Predictable Drug Release Profiles: Controlled Release: By understanding the specific properties of natural polymers such as amylose
