Title : Breakthrough, fast, precise and inexpensive 3D bioprinting of organoids and blood vessels
Abstract:
The calculated specifications of Roll Porous Scaffold (RPS) are orders of magnitude superior to all currently dominant 3D bioprinters in speed, volume, and print density without the use of expensive equipment and components: print density of 10−15 µm cells up to ~1.5×10^8 cells/mL. The use of 360 and 1200 dpi inkjet printheads immediately enables biomanufacturing with 10–30 µm cells in a single organoid with performance >1.8 L/hour for 15 µm layer thickness. The spongy bioresorbable ribbon for RPS technology is designed to solve the problems of precise placement, leakage and increasing in the number of instantly useable cell types. RPS based on widely available components and opens up new ways to improve healthcare without sending 3D bioprinters printers into space. Application of RPS 3D bioprinting are 1) Patch on an organ, a blood vessel for bypass or replacement, regenerative personal medicine, 2) Many parallel tests for targeted therapy, 3) Regularly rejuvenate even from a hundred years with the help of personal Hormone Replacement Therapy derived from printed endocrine glands for each of his DNA excluding rejection, but not creams, tablets, injections."
Audience Take Away Notes:
- Parallel testing of new drugs, substances not on animals, but using formed 3D biomodels "organ on a chip"
- Personalized and precision medicine with simultaneous testing of many methods and drugs of treatment, targeted therapy of a specific patient in vitro as if in vivo on 3D compositions of his personal cells and selection of the most effective with the lowest toxicity
- Overcoming the shortage of organs for implantation
