The release of Xenobiotics into the environment is a matter of global concern, as the harmful chemicals when reach in the environment; are stable over a prolonged period resulting in their accumulation in the environment. A gargantuan acceleration in the release of xenobiotics in the last decade has raised concerns over their occurrence in the soils and wastewaters posing imminence to the general public health and environment. Pharmaceuticals, pesticides, dyes are one of the major contributors to the unsustainable environment because they are malignant and hardly biodegradable in nature. To ensure the safe disposal and clean-up of environment the cost-effective and ecofriendly remediation technologies for degradation of these toxicants are urgently required. With the recent advances in biodegradation; researchers are showing interest in exploring bio-degradation techniques due to their efficiency, cost effectiveness and eco-friendly nature in combination with physio-chemical remediation techniques. Therefore, it’s extremely important to focus on various types of remediation processes available for the removal of xenobiotics with a special attention towards biodegradation for a green and sustainable environment.