Speaker at Global conference on Pharmaceutics and Drug Delivery Systems 2017 - Ulo Langel
Stockholm University, Sweden
Title : Transfection by cell-penetrating peptides

Abstract:

Recent data on mechanisms and applications of transfection strategies by cell penetrating peptides (CPP) are summarized on the variety of different oligonucleotide cargoes including plasmid, antisense and siRNA oligonucleotides. Introduction of PepFect and NickFect technologies for oligonucleotide transfection by transportan-based cellpenetrating peptides in vitro and in vivo is described. 403. Kurrikoff,K., Gestin,M., and Langel,Ü. (2016) Recent in vivo advances in cell-penetrating peptide-assisted drug delivery. Expert Opinion on Drug Delivery, 13(3), 373-387. Takeaway Notes •CPP technology for ON transfection, efficient ON transfection in vitro and in vivo, mechanisms of CPP transfection.

Biography:

Ülo Langel is a Professor at the Department of Neurochemistry, Stockholm University, and at the Institute of Technology, Tartu University. Prof. Langel has been selected as a Fellow Member of International Neuropeptide Society (1995), and is a member of Academia Europeaea. He is a coauthor of more than 400 scientific articles and 20 approved patents or patent applications.

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