Title : Effect of NSAIDs in the tooth movement in orthodontic treatment
Abstract:
Background: Patients undergoing tooth movement in orthodontics often utilize non-steroidal anti-inflammatory medications (NSAIDs) to alleviate inflammation and discomfort.[1-3] On the other hand, the orthodontic profession is still debating whether or not NSAIDs slow down or hinder tooth mobility.
Materials and Methods: About 60 mouths that needed their teeth moved participated in a randomized controlled experiment. There were two groups of patients: Group A received NSAIDs (ibuprofen, 400 mg), while group B received a placebo. Tooth movement was measured using digital calipers at baseline and then at intervals of 4 weeks over a period of 12 weeks.
Results: The mean rate of tooth movement in group A was 1.5 ± 0.3 mm per month, whereas in group B it was 1.8 ± 0.4 mm per month. Analysis of variance (ANOVA) showed a statistically significant difference (p < 0.05) in the rate of tooth movement between the two groups, with group B demonstrating faster tooth movement compared to group A.
Conclusion: The administration of NSAIDs during orthodontic treatment appears to have a modest but statistically significant inhibitory effect on the rate of tooth movement.Clinicians should consider the potential impact of NSAIDs on treatment outcomes when managing pain and inflammation in orthodontic patients.
