The full PDDS 2025 scientific program across 3 days — keynotes, oral presentations, and posters. Talks are ordered by program prominence within each day.
Day 1
- Keynote · Virtual
What Caffein brings to Paracetamol (Acetaminophen) in pain Management
Rassa Pegahi · UPSA, France
Background: Paracetamol is effective and safe in mild to moderate migraine attacks and episodes of tension-type headache (TTH). Few data are available on the use of paracetamol combined with caffeine, the aim of which…
- Keynote · Virtual
Enabling Active Pharmaceutical Ingredient Industry in Saudi Arabia
Waleed Mohammed Al Shaqha · Imam Muhammed Ibn, Saudi Arabia
The local production of active pharmaceutical ingredients (APIs) plays a vital role in strengthening national healthcare resilience by improving access to essential medicines and reducing dependence on imports and…
- Keynote · Virtual
Intelligent delivery of 5-fluorouracil using smart polymers
Mutaz S Salem · Jordan University of Science and Technology, Jordan
Colonic drug delivery systems have been utilized to treat a wide range of bowel illnesses, including colorectal cancer, ulcerative colitis, diverticulitis, Crohn's disease, and IBS. These systems can improve therapeutic…
- Keynote · Virtual
Astrotactin 2 as novel analgesic target candidate for cancer pain and opioid sparing: An exploratory genetic polymorphism analysis
Mizuho Sumitani · The University of Tokyo Hospital, Japan
Introduction: Cancer pain impairs not only physical functions but also social functions and roles. Neuronal protein astrotactin 2 (ASTN2) fulfills a function to regulate the release of neuronal adhesions to the glial…
- Keynote · Virtual
Evaluating maleic anhydride derivatives as linkers for Ph-sensitive drug release
Mateusz Mlynek · NanoSanguis S.A., Poland
Cancer remains a persistent global health challenge. Current therapeutic strategies often fall short due to the adaptive nature of tumor cells, highlighting the urgent need for innovative drug delivery approaches.…
- Keynote · Virtual
Evaluating maleic anhydride derivatives as linkers for Ph-sensitive drug release
Weronika Leszczynska · NanoSanguis S.A., Poland
Cancer remains a persistent global health challenge. Current therapeutic strategies often fall short due to the adaptive nature of tumor cells, highlighting the urgent need for innovative drug delivery approaches.…
- Keynote · Virtual
Evaluating Maleic Anhydride Derivatives as Linkers for Ph-Sensitive Drug Release
Julia Macyszyn · NanoSanguis S.A., Poland
Cancer remains a persistent global health challenge. Current therapeutic strategies often fall short due to the adaptive nature of tumor cells, highlighting the urgent need for innovative drug delivery approaches.…
- Keynote · Virtual
Liposomal formulation and quantitative HPLC analysis of random peptide mixtures for antibacterial drug development
Michal Szkop · NanoSanguis S.A., Poland
The rising antibiotic resistance among bacterial pathogens presents a growing global health concern, necessitating the exploration of novel therapeutic approaches. One promising alternative to traditional antibiotics is…
- Keynote · Virtual
Liposomal formulation and quantitative HPLC analysis of random peptide mixtures for antibacterial drug development
Marzena Kaliszewska Kozak · NanoSanguis S.A., Poland
The rising antibiotic resistance among bacterial pathogens presents a growing global health concern, necessitating the exploration of novel therapeutic approaches. One promising alternative to traditional antibiotics is…
- Keynote · Virtual
The Physicochemical, biopharmaceutical, and in vitro efficacy properties of diclofenac-loaded liposomes
Iria Naveira Souto · Reig Jofre | University of Barcelona, Spain
Diclofenac-loaded liposomes were developed as a tool to treat inflammatory skin disorders. Topical administration of this molecule is a challenge that can be addressed by encapsulation into drug delivery systems. The…
- Oral · In-Person
Ectopically expressed olfactory receptors as an untapped family of drug targets and discovery of agonists and antagonists of OR51E1, an understudied G Protein-Coupled Receptor
Vladlen Slepak · University of Miami School of Medicine, United States
Over 30% of pharmaceuticals act on G Protein-Coupled Receptors (GPCRs), the largest family of human genes (~800). About 50% of GPCRs (~400) are Olfactory receptors (ORs); these GPCRs were originally discovered in the…
- Oral · In-Person
Innovative development and delivery of biologics for chronic obstructive pulmonary disease
Yong Xiao Wang · Albany Medical College, United States
It is well known that chronic obstructive pulmonary disease (COPD) is a common and devastating lung disease with a high mortality. The current therapeutics for this disease are neither specific nor very effective.…
- Oral · In-Person
Personalized and Precision Medicine (PPM) as a unique healthcare model through de-sign-inspired biotech- & biopharma-driven applications and upgraded business mar-keting to secure the human healthcare and biosafety
Sergey Suchkov · N D Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, InMedStar and Biona, Russian Federation
Traditionally, a disease has been defined by its clinical presentation and observable characteristics, not by the underlying molecular mechanisms, pathways and systems biology-related processes specific to a particular…
- Oral · In-Person
Macitentan/tadalafil combination– An additional value in pharmacotherapy of pulmonary arterial hypertension
Miroslav Radenkovic · University of Belgrade, Serbia
Pulmonary arterial hypertension (PAH) remains a devastating disease with high morbidity and mortality. It is uncommon, progressive and life-threatening blood vessel disorder differentiated by the constriction of minor…
- Oral
Identification of sulfonamide-based aromatase inhibitors in the breast cancer research
Barbara De Filippis · University of Chieti, Italy
Breast cancer (BC) represents the type of cancer that most frequently affects women and one of the leading causes of death among females worldwide. Approximately 70% of cases of BC are estrogen dependent (Hormone…
- Oral
Pharmacology of chlorphenamine and pseudoephedrine use in the common cold
Rassa Pegahi · UPSA, France
The common cold is the most frequent upper respiratory viral infection. Although benign, it represents a high socioeconomic burden. Many over-the-counter drugs are available to manage the symptoms of this condition…
- Oral
Antibody-proteases as translational tools of the next-step generation to be applied for biopharmacy-related and precision medical practice
Sergey Suchkov · N D Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, InMedStar and Biona, Russian Federation
High impact of Ab-proteases is valuable to monitor both clinical and subclinical courses of chronic autoimmune inflammation to predict stepwise transformations of the course, starting from the pre-illness and to…
- Oral
Is paracetamol (acetaminophen) still a first line option for pain and fever in paediatrics?
Rassa Pegahi · UPSA, France
Background and Aim: Effective analgesia and fever management in children from birth remain crucial. This study aims to provide updated insights into the use of paracetamol in pediatric care. Methods: A comprehensive…
- Oral
Innovations in rivastigmine delivery: Nanostructured lipid carriers encapsulated in microneedles for enhanced transdermal delivery
Shereen M Assaf · Jordan University of Science and Technology, Jordan
Rivastigmine (RHT), used in the management of Alzheimer's disease, reduces acetylcholine degradation and enhances the cognitive function. Challenges in RHT delivery arise due to its limited ability to permeate the…
- Oral
Assessment of inulin content in Arctium Lappa l. root extract: Potential for nutritional and medicinal applications
Elena Donici · State University of Medicine and Pharmacy, Moldova, Republic of
Inulin, scientifically known as α-D-glucopyranosyl-β-D-fructofuranosyl-D-fructofuranoside, is a natural polysaccharide with diverse biological activities. It is widely used in the food and pharmaceutical industries as a…
- Oral
Evaluating Aronia Melanocarpa varieties for pharmaceutical applications based on polyphenolic content and antioxidant activity
Iulia Bozbei · State University of Medicine and Pharmacy, Moldova, Republic of
In recent years, the global community has been actively seeking plant-based sources with therapeutic and nutritional potential. The fruits of Aronia melanocarpa are widely recognized and utilized for these purposes. The…
- Oral
Therapeutic efficacy of nanostructured lipid carriers co-loaded with simvastatin and adenosine (NLC- SA) in a human epidermal model of diabetic chronic wound
Regina Gomes Dare · University of São Paulo, Brazil
Chronic wounds are characterized by persistent inflammation, elevated oxidative stress, and impaired tissue repair, posing a major clinical challenge, particularly in diabetic patients. In this study, we established a…
- Oral
Advances in hydrophilic drug delivery: Encapsulation of biotin in alginate microparticles
Iria Naveira Souto · Reig Jofre | University of Barcelona, Spain
The encapsulation of hydrophilic drugs within microparticles has gained significant interest in drug delivery systems due to their potential to improve the stability, bioavailability, and controlled release of…
- Oral
Formulation and characterization of buccal films based on sodium alginate and chitosan for using in parkinson's disease
Krisztian Pamlenyi · University of Szeged, Hungary
Parkinson's disease is the second most common neurodegenerative disease in the world, 16-20 thousand people suffer from this disease in Hungary and more than 10 million people worldwide. The symptoms can be various…
- Oral
The promise of nanotechnology in personalized & precision medicine: Drug discovery & development being partnered with nanotechnologies via the revolution at the nanoscale
Sergey Suchkov · N D Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, InMedStar and Biona, Russian Federation
A new systems approach to subclinical, predictive and/or diseased states and wellness resulted in a new Hi Tech trend in the healthcare services, namely, personalized and precision medicine (PPM). Meanwhile, despite…
- Oral
GastroPlus® and ADMET Predictor driven predictive model for pharmacokinetic parameters of ENDOL® immediate-release capsule
Ayse Nur Oktay · University of Health Sciences-Gulhane Faculty of Pharmacy, Turkey
In silico tools have become indispensable for preclinical assessment of pharmacokinetic parameters of drug. Several commercial software platforms, such as GastroPlus®, PK-Sim®, Stella®, and GISim®, offer comprehensive…
- Oral
Enhancing delivery of biopharmaceutics classification system class ii drugs through a novel carrageenan-alginate-oleogel matrix: A case study on praziquantel for improved therapeutic efficacy
Consolata Nsanzubuhoro · Stellenbosch University, South Africa
Schistosomiasis, a waterborne neglected tropical disease (NTD) prevalent in sub-Saharan Africa and South-East Asia significantly impacts socio-economic development. Praziquantel (PZQ) serves as the primary treatment…
Day 2
- Keynote
Analytical strategies for solid-state forms in drug development
Maria Cristina Gamberini · University of Modena and Reggio Emilia, Italy
The solid-state characterization of pharmaceutical compounds plays a pivotal role in understanding and controlling the physical and chemical properties of active pharmaceutical ingredients (APIs) and excipients. This…
- Keynote
Understanding drug transport in plasma: The role of protein binding
Saad Tayyab · UCSI University, Malaysia
Understanding drug transport in plasma is pivotal to optimizing therapeutic outcomes, as it governs drug distribution, efficacy, and clearance. A key factor in this process is protein binding, where drugs reversibly…
- Keynote
Design and evaluation of exo-itc: A bilayer fibrous system for controlled exosome delivery in dermatological applications
Luis Jesus Villarreal Gomez · Universidad Autónoma de Baja California, Mexico
This research explores the creation of a novel exosome delivery platform, termed Exo-ITC, tailored for use in dermatology. Exosomes, as extracellular vesicles, are pivotal in intercellular communication and exhibit…
- Keynote
Mathematical modeling the disc diffusion test: Antibacterial activity of copper-doped SnO2
Paulo Cesar De Morais · Catholic University of Brasilia, Brazil
In this keynote talk, the traditional disc diffusion-test bioassay is revisited within the perspective of using a mathematical approach grounded on the standard as well as on the modified Hill model. Importantly, the…
- Keynote
Emerging formulation and delivery applications of vitamin E TPGS
Andreas M Papas · Antares Health Products, United States
Vitamin E TPGS (d-α-tocopheryl polyethylene glycol 1000 succinate) combines the functions of solubilizer, emulsifier, and absorption enhancer of lipophilic and poorly soluble drugs. In addition, it enhances drug…
- Keynote
Medical liver biopsy: Toward a personalized approach
Consolato M Sergi · University of Alberta, Canada
Introduction: Metabolic-(non-alcoholic) associated fatty liver disease (MAFLD/NAFLD) has increasingly become a worldwide epidemic. It has been suggested that renaming NAFLD to MAFLD is critical in identifying patients…
- Keynote · In-Person
Eco-friendly hydrotropic technology in pharmaceutical analysis precluding the use of hazardous organic solvents
R K Maheshwari · Sri Govindram Seksaria Institute of Technology and Science, India
A large number of organic solvents (chloroform, hexane, methanol, dimethyl formamide, ethanol, benzene, toluene, carbon tetrachloride, methylene chloride, acetonitrile etc) are employed in various types of…
- Keynote · In-Person
Diabetes risk stratification using self-reported health indicators: a machine learning and explainability
Tanuja Tummala · Harrisburg University of Science and Technology, United States
This study presents a machine learning approach to classify diabetes status using the CDC BRFSS 2015 dataset, which includes over 250,000 self-reported health records across 22 variables. The goal was to develop a…
- Keynote · In-Person
The effect of finasteride on parity rates in drosophila melanogaster
Dominic Sandell · Embry-Riddle Aeronautical University, United States
Finasteride has been used to treat male pattern baldness and benign prostate hyperplasia, and could potentially treat female pattern baldness and polycystic ovary syndrome. However, the drug has the unintentional side…
- Poster
Psychedelic drugs – safety problems in pregnancy
Anna W Sobanska · Medical University of Lodz, Poland
Psychedelic drugs acting upon the serotonergic receptors are currently considered to be not only substances of abuse, but also the hope of new therapies of mental problems such as depression, PTSD and eating disorders…
- Poster
Morphological versatility of hybrid systems: Mimicking the self-assembly of natural structures
Natassa Pippa · University of Athens, Greece
The morphology of nanosystems is one of the Critical Quality Attributes (CQAs) of the nanoformulations, affecting the interactions of cellular membranes as well as the release of the encapsulated active substances.…
- Poster
Drug development - Importance, trends and digital transformation
Gurpreet Singh · IQVIA, United Kingdom
The entire process of developing a drug from preclinical research to marketing can take approximately 12 to 18 years and often costs well over $1 billion. Global Top Pharmaceutical Companies based on projected R&D…
- Poster
Biodegradable ribbon for Roll Porous Scaffold 3D bioprinting technology
Vyacheslav R Shulunov · Institute of Physical Materials Science of the Siberian Branch of the Russian Academy of Science, Russian Federation
The advantages of 3D bioprinting, tissue engineering and regenerative medicine represent a powerful potential for everyone who wants to always be healthy, young or rejuvenate. Overcome the shortage of organs for…
- Poster
Cu/N/Pd /Ni nanocomposites from wastes Printed circuit boards (PCBs) to remove endocring disruptors
Rukiye Oztekin · Dokuz Eylul University, Turkey
Dibutyl phthalate and nonylphenol from endocring disruptors were removed photocatalycally with nanocomposites derivated from printed circuit board wastes. These wastes represent 3% of the total mass of waste electric…
- Poster
Nanoparticle mediated Drug Delivery system in Cerebrovascular disorders
Raja Chakraverty · Indian Council of Medical Research, India
In the realm of cerebrovascular incidents, the safeguarding of cerebral vasculature is recognized as a paramount goal. This talk will focus on the recent advances made in the domain of nanoparticle mediated drug…
- Poster
Mechanistic insights into phlorizin’s multi-target potential in Alzheimer’s disease: A network pharmacological and in-vivo study
Nilay Solanki · Charotar University of Science and Technology, CHARUSAT Campus, India
This study investigated the therapeutic potential of phlorizin for Alzheimer's disease (AD) using an integrated computational and experimental pharmacology approach. The research aimed to determine how phlorizin…
- Poster
Design and computational analysis of a peptide analogue with a WXXW motif: A membrane-active and reversible drug binding peptide to overcome cancer drug resistance
Nurul Ain binti Mohammad Hamdi · University of Manchester, United Kingdom
Membrane-active peptides are known for their ability to transport therapeutic agents across cellular membranes, thereby enhancing intracellular delivery. In this study, we designed a membrane-active peptide analogue by…
- Poster
Lysozyme – enzybiotic as promising weapon against antimicrobial resistance
Meliha Mehic · Bosnalijek Pharmaceutical Industry, Bosnia and Herzegowina
Antibiotic resistance is a global problem. The incidence and prevalence of antimicrobial-resistant-bacterial infections has attained incongruous levels during 21 st century and threatens global public health as a silent…
- Poster
Acetaminophen-Over the counter Drug: Applications and Safety Concerns
Neha Agarwal · Navyug Kanya Mahavidyalaya, India
Pharmaceuticals have undoubtedly lengthened life spans, cured millions from deadly diseases, and made life comfortable and free from pain. This very success has now led to their emergence as rapidly growing…
- Poster
Formulation and evaluation of the Pilosomes as Drug Delivery System (PDDS)
Dharmendra Kumar · Swami Vivekanand Subharti University, India
One of the primary challenges in pharmaceutical dosage form development is the poor solubility of certain drugs, particularly those classified as Biopharmaceutics Classification System (BCS) Class IV. These drugs…
- Poster
Therapeutic drug development using biopolymer degrading enzymes
Deepika Sharma · CGC Mohali Punjab, India
Biopolymers play critical roles in structure, function, storage, and regulation of biological processes in living beings. Bacterial biopolymers, such as alginate, lipopolysaccharides (LPS), polyhydroxyalkanoates (PHAs)…
- Poster
Ayurvedic bhasmas as a nano medicines for the human kind
Prashant Sakharam Bhokardankar · Datta Meghe Ayurvedic Medical College Hospital and Research Centre, India
Mineral and metallic nanomedicines are a precious resource found in the Ayurvedic medical system. Rasashastra is an Ayurvedic branch that deals with the preparation and therapeutic use of nanomedicines. A weak…
- Poster
C. elegans as a platform for studying neurodegenerative diseases: Identification of antioxidants as therapeutic agents
Maria Jose De Rosa · Universidad Nacional del Sur, Argentina
The increase in life expectancy has led to a rise in age-related disorders, including neurodegenerative diseases (NDs) such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease (HD). Oxidative…
- Poster
Isolation and evaluation of antioxidant and cytotoxic activity of 2',4'-dihydroxy-3',5'-dimethyl-6'-methoxychalcone from the ethyl acetate extract of the leaves of Syzygium balsameum (Wight) Wall. ex Walp
Mst Rozina Parul · Gono University, Bangladesh
Syzygium balsameum Wight is shrubs or trees of the Myrtaceae family. The present study reports on the based-onand isolation of a flavonoid 2',4'-dihydroxy-3',5'-dimethyl-6'-methoxychalconefrom the leaves of Syzygium…
- Poster
Biotechnological methods for optimizing secondary metabolite production in plants for pharmaceuticals
Ali Yetgin · Institute of Nature and Applied Sciences, Department of Biotechnology, Adana, Turkey, Turkey
The escalating demand for pharmaceuticals derived from natural sources has catalyzed extensive research aimed at optimizing the synthesis of secondary metabolites in plants. Secondary metabolites, including alkaloids…
- Poster
Impact of histone deacetylase isoform on the effectiveness of immune checkpoint therapy
Ravi P Sahu · Wright State University, United States
While multiple therapeutic options exist for melanoma, their overall responses in the majority of patients remain relatively low due to the interference of counter-regulatory mechanisms. This indicates the need to…
- Poster
Green chemistry, honey-based synthesis of silver nanoparticles and the evaluation of their antibacterial activities
Rose Stiffin · Chair, United States
Silver nitrate (AgNO3) nanoparticles have gained significant attention for their antimicrobial and anticancer properties. This study presents a green, sustainable, and cost-effective method for synthesizing AgNO 3…
- Poster
Pharmacometrics: Evolution, current applications, and future horizons in drug development and personalized medicine
Rama Rao Nadendla · Chalapathi Institute of Pharmaceutical Sciences, India
Pharmacometrics, defined as the quantitative science of analyzing, modeling, and interpreting pharmacological data, has undergone a remarkable transformation from its foundational roots in classical pharmacokinetics…
- Poster
Aloe leaf juice as a basis for antiseptic-enhanced wound healing agents in wartime
Roman Lysiuk · Danylo Halytsky Lviv National Medical University, Ukraine
In wartime, the need for effective wound healing, anti-inflammatory and antibacterial agents becomes particularly urgent. Herbal remedies are of special interest due to their affordability, broad pharmacological…
- Poster
Impact of sugars on electrospray-dried peptide/protein powder formulations
Teresa Carvajal · Purdue University, United States
Electrospray drying is an emerging technique gaining attention in the pharmaceutical industry, particularly for the formulation of biologics and nanoparticles. It enables the production of particles with controlled…
- Poster
Quality assurance framework for implementing therapeutic drug monitoring in preterm infants: Enhancing safety and precision in neonatal care
Bindiya Chauhan · SGT University, India
Therapeutic drug monitoring (TDM) is essential in preterm infants due to their unique pharmacokinetics and heightened susceptibility to drug toxicity and therapeutic inefficacy. This study proposes a structured quality…
Day 3
- Keynote
Eliminating implant failure in humans with nanomaterials: 30,000 cases and counting
Thomas J Webster · Hebei University of Technology, United States
Nanomedicine is the use of nanomaterials to improve disease prevention, detection, and treatment which has resulted in hundreds of FDA approved medical products. While nanomedicine has been around for several decades…
- Keynote
Managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel · University of Regensburg, Germany
For realizing pervasive and ubiquitous health and social care services, health and social care system have to undergo an organizational, methodological and technological transformation towards personalized…
- Keynote
Search for novel biomarkers and therapeutic targets for inflammatory disease
Madhav Bhatia · University of Otago, New Zealand
Hydrogen sulfide is a toxic gas, which is an environmental and industrial pollutant. In recent years, however, it has been shown that this gas is also synthesized in the body, and acts as a potent vasodilator. Substance…
- Keynote
Abuse-deterrent dosage form technique utilizing a fusion of innovative pharmaceuticals and ion exchange resin
Bhupendra Gopalbhai Prajapati · Parul University, India
Prescribed drug abuse denotes the potential misuse of pharmacological formulations. Many regulatory agencies are working to improve rules for current and future drug formulations by using some level of abuse deterrent…
- Keynote
In silico analysis for the screening and selection of repurposed drugs and mitochondrial targets for drug development and delivery for OSCC therapy
Suresh P.K · VIT University, India
Globally, Oral Squamous Cell Cancer(OSCC) is a significant public health burden in terms of health care costs as well as lost man-hours and school-hours. This form of neoplasia ranks 3 rd both in terms of the number of…
- Keynote
FAST nanotechnology: A novel platform for drug development and beyond
Stephen Hsu · Augusta University, United States
The bioavailability crisis remains a major bottleneck in drug development, particularly for hydrophobic compounds such as paclitaxel and medroxyprogesterone acetate (MPA). Paclitaxel, a first-line chemotherapeutic, is…
- Keynote
Development of novel drug delivery pathways enabled by perillyl alcohol (NEO100), a monoterpene with multifaceted biomedical applications
Axel H Schonthal · University of Southern California, United States
Perillyl alcohol is a naturally occurring monoterpene related to limonene. We have synthesized a clinical-grade version, called NEO100 (NeOnc Technologies, Inc., Los Angeles, California), which has revealed a variety of…
- Keynote
Precision oncology and personalised medicine: Innovative technology for the treatment of colorectal cancer
Huiqin Yang · ICON Clinical Research Ltd, United Kingdom
Precision oncology plays an essential role for the treatment of solid cancers. Colorectal cancer has emerged as a disease condition where abnormal genetic mutations occur in a group of colorectal cancer patients.…
- Poster
Drug delivery strategies for the management of microbial infections and wound healing
Lisa Marinelli · University “G. d’Annunzio” of Chieti-Pescara, Italy
Infected and chronic wounds represent a significant healthcare challenge due to their complex healing processes and the presence of persistent microbial biofilms that interfere with tissue repair. Conventional…
- Poster
Medication errors: Detection, impact, and risk reduction through pharmacovigilance
Punam Kumari · Pharmacovigilance Consultant, Clinexel, United Kingdom
Medication errors are a leading cause of preventable harm in healthcare systems worldwide, with significant implications for patient safety and therapeutic outcomes. Within the European Union (EU), addressing medication…
- Poster
From self-assembly to healing: Engineering ultra-small peptides into supramolecular hydrogels for controlled drug release
Marilisa Pia Dimmito · University “G. d’Annunzio” of Chieti-Pescara, Italy
The objective of this study was to assess the suitability of novel mucoadhesive hydrogel platforms for delivering therapeutics targeting gastrointestinal (GI) disorders. To this end, we developed and characterized novel…
- Poster
Study of serum adiponectin and hsCRP in diabetic patients
Preeti Sharma · Autonomous State Government Medical College, India
Adiponectin, a major cytokine from adipose tissue and hsCRP, a well established marker of inflammation are known to be associated with increased risk of cardiovascular disorders (CVD), when levels fluctuate from the…
- Poster
Cannabinoid acids for the treatment of multiple sclerosis
Sigal Fleisher Berkovich · Ben-Gurion University of the Negev, Beer-Sheva, Israel
Penetration of immune cells into the brain, activation of glia and secretion of inflammatory mediators like cytokines and free radicals like nitric oxide (NO) play key role in Multiple sclerosis (MS); an autoimmune…
- Poster
Chemo-enzymatic synthesis of bridged nucleosides
Rajesh Kumar · B.R.A. Bihar University, India
Over two decades, a large number of nucleosides have been synthesized, which demonstrated potent antiviral and antitumour activities and have become cornerstones of treatment for patients with cancer or viral…
- Poster
Epigenetics in drug development: Unlocking novel therapeutic strategies for precision medicine
Anil Pareek · Anand Pharmacy College, India
Epigenetics, the study of heritable changes in gene expression that do not involve alterations to the DNA sequence, has revolutionized our understanding of complex biological processes and disease mechanisms. In drug…
- Poster
Impact and challenges supply chain realibity in pharmaceutical process development
Nizama Hodzic · Bosnalijek Pharmaceutical Industry, Bosnia and Herzegowina
Drug delivery systems as a technological system formulate and store drug molecules into suitable forms of medications. Effective process development plays a key role in mitigating risk, accelerating time-to-market, and…
- Poster
Development, pharmaceutical analysis and invitro evaluation of modified herbal fumigation formulations
Parikshit R Shirode · Parul University, India
Ayurveda is science of the life. Maintenance of the health of healthy individuals and Treatment of the diseased are the main principles of Ayurveda management. Acharya Sushruta, The Father of Surgery, explained…
- Poster
Novel nucleobase–2-oxindole–heterocyclic hybrids as selective cell cycle regulators with potential anticancer activities
Tarek Aboul Fadl · Assiut University, Egypt
Cancer remains a global health threat despite advances in research and technology. According to International Agency for Research on Cancer, the cancer burden will increase by about 77% by 2050, further straining health…
- Poster
Pharmacopollution: Trends over time
Andre Luiz Pereira · Escola de Saúde Pública do Estado de Minas Gerais (ESP-MG), Brazil
Pharmacopollution is a public health and environmental outcome of some active pharmaceutical ingredients(API) and endocrine-disrupting compounds (EDC) dispersed through water and/or soil. Its most important sources are…
- Poster
Personalized medicine: Tailoring drug delivery systems for targeted therapeutic efficacy
Monica Arora · Villa College, Maldives
Personalized medicine has emerged as a transformative approach in healthcare, focusing on optimizing therapeutic outcomes by tailoring drug delivery systems to individual patient needs. Traditional drug administration…
- Poster
Comprehensive analytical and bioanalytical method validation for the quantification of linagliptin and empagliflozin in fixed-dose combinations
Khagga Bhavyasri · Osmania University, India
A comprehensive bioanalytical method was developed and validated for the simultaneous estimation of Linagliptin and Empagliflozin in fixed-dose combination formulations using UV spectrophotometry. This study emphasizes…
- Poster
Cholesterol lowering and regulation of inflammation by PCSK9
Maria Borrell · Sant Pau Research Institute, Spain
Atherosclerosis, the leading cause of cardiovascular diseases, is driven by high blood cholesterol levels and chronic inflammation. The disruption of the hepatic interaction between Proprotein Convertase…
- Poster
Analytical methods based on liquid chromatography tandem mass spectrometry for the detection of genotoxic nitrosamine impurities
Phanikumar Reddy Satti · Veranova L.P., United States
The presence of genotoxic impurities like nitrosamine in pharmaceutical products has become a pressing global safety concern due to their potential carcinogenic and mutagenic e8ects. NAs, particularly N-nitroso…
- Poster
The critical role of lung safety in regulatory approval of systemic inhalation delivery products
Xiaodong Li · LUXENA Pharmaceuticals, Inc., United States
In systemic inhalation delivery, the respiratory tract is used as a route of administration, allowing the active ingredient to enter the blood circulation directly through the alveoli. It is not for lung diseases, but…
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