The full PDDS 2022 scientific program across 2 days — keynotes, oral presentations, and posters. Talks are ordered by program prominence within each day.
Day 1
- Keynote
Drug Delivery to the Brain using Engineered Protein Capsules (EnPCs®)
Victoria Demina · NEUWAY Pharma GmbH, Germany
The blood brain barrier (BBB) is both a blessing and a curse: On the one hand, the tightly connected endothelial cells covering the cerebral blood vessels protect the brain from harmful large molecules. On the other…
- Keynote
Arsenate target specific cell death mechanism in normal and tumoral breast cancer cell lines
Cornelia Braicu · Iuliu Hațieganu University of Medicine and Pharmacy, Romania
Arsenate was demonstrated to be implicated in a wide range of cellular and molecular pathways. These multiple actions of arsenate highlight the need for additional mechanistic studies to determine which actions mediate…
- Keynote
Cardiac myosin inhibitors – New pharmacological approach for obstructive hypertrophic cardiomyopathy treatment
Miroslav Radenkovic · University of Belgrade, Serbia
The modern knowledge of hypertrophic cardiomyopathy (HCM) rapidly evolved over the past twenty years, where the thorough understanding of HCM pathophysiology, combined with innovative therapeutic solutions, finally…
- Oral · In-Person
Development and Evaluation of Structured Strategic Approach for successful accomplishment of Risk-Based Monitoring model from clinical trial inception to completion at clinical trial organization.
Heema Desai · Texila American University, India
International Conference on Harmonization guideline E6 requires clinical trial sponsors to conduct monitoring oversight to ensure the protection of rights, safety and welfare of the clinical trial subjects. In 1988, the…
- Oral · In-Person
Latest trends in Bio-degradation of Xenobiotics for cleaning up the environment
Neha Agarwal · Navyug Kanya Mahavidyalaya, India
The release of Xenobiotics into the environment is a matter of global concern, as the harmful chemicals when reach in the environment; are stable over a prolonged period resulting in their accumulation in the…
- Oral · In-Person
Acetylcholinesterase and ATPases: Targets of biologically active compounds
Mirjana B. Colovic · University of Belgrade, Serbia
Acetylcholinesterase is a serine hydrolase whose key biological role is the termination of impulse transmission at cholinergic synapses by rapid hydrolysis of the neurotransmitter acetylcholine. The reversible…
- Oral · In-Person
Understanding the issues with recruitment in pediatric clinical trials in India as cited by key stake holders and to draw down the strategies for better recruitment
Tanvi S Kabre · Texila American University, India
A steep rise is seen in conduct of clinically trials not just globally but in India as well over the years. Through this pharma industry is striving to serve high-quality treatments and procedure options catering to all…
- Oral · In-Person
An insight to anti-acne potentials: In-vitro, ex-vivo and in-vivo models
Deepinder Singh · Chitkara University, India
Acne is the 8 th most commonly prevailing chronic skin disorder affecting more than 9.4% population worldwide. Its pervasiveness has been predominant in juveniles especially in males during adolescence. However, acne…
- Oral · In-Person
Advanced cancer diagnosis and therapy using carbon nanodots/tetrapyrrolic macrocycles conjugates
Gil Goncalves · University of Aveiro, Portugal
Carbon is one of the most relevant elements on earth to all forms of life and presents a wide range of natural allotropic forms with high economic potential. Inspired by nature, scientists started to design synthetic…
- Oral · In-Person
API characterization – why dissolution testing can help you learn more about Active Ingredient.
Samir Haddouchi · Sotax Pharma Services, France
Dissolution is a critical parameter of pharmaceutical dosage forms. It is indeed an extremely powerful tool to acquire knowledge about pharmaceutical products. The dissolution techniques can also be used to learn more…
- Oral · In-Person
Chlorine dioxide as root canal irrigation solution in endodontic treatment
Hilal Erdogan · Nevsehir University, Turkey
Root canal treatment applied to inflamed teeth is a dental treatment method that aims to keep the natural tooth in the mouth by fulfilling its functional, phonetic, and aesthetic functions. For this purpose, the removal…
- Oral · In-Person
Prodrugs of non-steroidal anti-inflammatory drugs (NSAIDs) and Amino acid esters as novel non-cyclooxygenase inhibitors for colorectal cancer chemoprevention
Tarek Aboul Fadl · Assiut University, Egypt
A structure-based medicinal chemistry strategy was applied to design new NSAID prodrugs that show growth inhibitory activity against human colon tumor cells through cyclooxygenase (COX)-independent mechanism. In vitro…
- Oral · In-Person
Continuous glucose monitors impact on glycemic control among American Indian and Alaskan Natives: Single center, pre- post- comparison
Alena Korbut · IHS/Cherokee Nation, United States
Introduction: Continuous glucose monitors (CGM) technology provides insight into a complete picture of a person’s blood glucose levels throughout the day and the full effect insulin has on the blood glucose trends. The…
- Oral · In-Person
Formulation and evaluation of Escitalopram loaded bio nanosuspension for brain specificity.
Deepika Raina · Graphic Era Hill University, India
In the United States, it is estimated that depression costs the country over $210 billion each year in lost productivity, health care costs, and absenteeism. It is estimated that between 1 and 3 percent of adults suffer…
- Oral · In-Person
Medicine waste pollution: A Brazilian view about pharmacopollution and public health
Andre Luiz Pereira · Escola de Saúde Pública do Estado de Minas Gerais (ESP-MG), Brazil
Pharmacopollution is a public health and environmental outcome of some active pharmaceutical ingredients(API) and endocrine-disrupting compounds (EDC) dispersed through water and/or soil. Its most important sources are…
- Oral · In-Person
Understanding ABC transporters to navigate human diseases
Ruchika Bajaj · University of California San Francisco, United States
Membrane proteins constitute 30% of genome in organisms and are involved in numerous physiological processes. ABC transporters is a class of membrane proteins which are ubiquitously present in all organisms, bind and…
- Oral · In-Person
APE-1 redox activity inhibition impacts dopaminergic system in inflammatory pain condition
Amira Zaky · Alexandria University, Egypt
Apurinic/Apyrimidinic Endonuclease 1/Redox Effector- 1 (APE1/Ref-1) is a negative regulator of inflammatory response via several mechanisms in neuronal cells. APE1’s redox activity stimulates the DNA-binding activity of…
- Oral · In-Person
Critical issues related to plant and pharmaceutical biotechnologies to achieve nations' development and welfare
Eman A. Alam · Al-Azhar University, Egypt
In recent years, biotechnology has expanded too much in its scope and applicability. Now biotechnology is well known for its great role in the field of medicine and is also used in many other areas such as food and…
- Oral · In-Person
Development and in-vitro evaluation of K-carrageenan bead for sustained delivery of Repaglinide
Divya Sharma · Delhi Pharmaceutical Sciences and Research University, India
Controlled drug delivery systems release drugs at a pre-set pace in order to maintain a constant drug concentration over a set period of time while minimising side effects. Repaglinide is a low-dose drug that is…
- Oral · In-Person
Method for tailoring diabetes simulator for optimal in silico trial in target populations
Roberto Visentin · University of Padova, Italy
Treatment of type 2 diabetes (T2D) involves a variety of medications, related to the stage of T2D progression. In silico trials can be helpful in this context, speeding up the drug development process and supporting…
Day 2
- Keynote
Mucoadhesive systems for the fast delivery of drugs
Luis Jesus Villarreal Gomez · Universidad Autónoma de Baja California, Mexico
The necessity of new systems for drug delivery in children and specific procedures is clearly needed, in the case of children the difficulty of the correct dose administration is a problem when the drug carrier is not…
- Oral · In-Person
Hydrogen Sulfide: A Stinky Gas….. and Novel Therapeutic Target for Inflammatory Disease
Madhav Bhatia · University of Otago, New Zealand
Inflammation is a normal adaptive response to traumatic, infectious, post-ischemic, toxic or autoimmune injury. Uncontrolled inflammation, however, results in disease, and most of diseases have been shown to have an…
- Oral · In-Person
Vaccines against rotavirus, data based on a study for safety and efficacy
Merita Kucuku · Freelance consultant, Albania
Vaccines and vaccination are important for the prevention of infectious diseases. In the history of vaccination, we have savings of lives of people of different ages from children aged 0 days and the very old people.…
- Oral · In-Person
Self microemulsifying systems based topical lipstick of antifungal agent
Bhupendra Gopalbhai Prajapati · Parul University, India
Self-emulsifying system-based lipstick may prove to have potential of enhancing the moisturizing characteristics and deliver the hydrophobic drug antifungal drugs for the treatment of lip fungal infections. In this…
- Oral · In-Person
Immune checkpoint inhibitors (ICIs) and immune-related adverse drug reactions: Focus on their neurotoxicity
Liberata Sportiello · University of Campania “L. Vanvitelli”, Italy
Harnessing the power of the immune system to target cancer has been the aim of scientific research for over centuries. The irruption of immune checkpoint inhibitors (ICI) in 2011 has changed the therapeutic landscape of…
- Oral · In-Person
Catecholase activity, electrochemistry and magnetic behavior of a azido bridged dinuclear copper(II) complex of a phenol based‘‘end-off” compartmental ligand
Prateeti Chakraborty · Bangabasi College, India
A dinuclear Cu(II) species [Cu 2 L 2 (H 2 O) 2 (N 3 )](NO 3 ) 2 (L = 2,6-bis(N-ethylpyrrolidine-iminomethyl)-4-methyl-phenolato) where two Cu centers are bridged by phenoxido and l1,1-azido bridges with Cu–Cu separation…
- Oral · In-Person
Formulation and optimization of self micro emulsifying drug delivery system (SMEDDS) of Clopidogrel Bisulfate by using D-Optimal mixture design
Maimuna Fatima · G. Pulla Reddy College of Pharmacy, India
The present work aims to develop a self-micro emulsifying drug delivery system (SMEDDS) to improve in-vitro dissolution of Clopidogrel Bisulfate an Anti-platelet agent, belonging to BCS class II. Initially, solubility…
- Oral · In-Person
Novel connective tissue growth factor (CTGF)-loaded alginate and alginate sulfate/polycaprolactone nanoparticles with promising wound healing activity
Mia Karam · American University of Beirut, Lebanon
Diabetes is a metabolic disorder characterized by hyperglycemia and affecting more than 460 million people worldwide. Uncontrolled diabetes can lead to secondary complications such as non-healing diabetic foot ulcers…
- Oral · In-Person
Monograph on Butea monosperma (Palas): An important plant for Lac cultivation
Rakhi Mishra · Dr. D.P. Rastogi Central Research Institute of Homoeopathy, India
Butea monosperma (Family Fabaceae) popularly known as ‘dhak’ or ‘palas’, commonly known as ‘Flame of forest’ is an important plant and is extensively utilized for lac cultivation. Lac cultivation plays an important role…
- Oral · In-Person
A novel drug delivery system: Fast dissolving film containing niosomes
Nikita Kale · Oriental University, India
FDF is also knows as oral wafers which is bunch of thin polymeric film which is now gaining widespread interest in pharmaceutical industry. It is novel formulation and now accepted by various customers for supplying…
- Oral · In-Person
Future needs for inhaled drug delivery
Adam Sikora · Nicolaus Copernicus University, Poland
Asthma and COPD are among the most common chronic non-communicable diseases. Many different environmental and individual factors are involved in their development. The main goals of treatment are to prevent symptoms of…
- Oral · In-Person
Aryl Amine content determination in different Indian brands of hair dyes by analytical techniques
Khagga Bhavyasri · Osmania University, India
Paraphenylenediamine (PPD) is a chemical substance that is used in hair dye because it is a permanent dye that gives a natural look, and the dyed hair can also be shampooed or permed without losing its colour.…
- Oral · In-Person
Formulation and evaluation of tablet containing different variety of native starches
Shiv Kumar · Maharaja Ranjit Singh Punjab Technical University, India
Starch is known to be one of the most abundant carbohydrate molecules found in tropical roots and tubers, grains, and cereals. Various botanical sources of starch, including maize, potato, corn, wheat, etc., have been…
- Oral · In-Person
Synthesis, characterization, biological and molecular docking studies of (Z)-N-substituted-4-(pyridin-2-yl)-6-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-2-amine
Mohammad Arshad · Shaqra University, Saudi Arabia
A series of fifteen (Z)-N-substituted-4-(pyridin-2-yl)-6-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-2-amine, was designed, screened computationally and synthesized. Structures of the compounds ( 1-15 ) were elucidated…
- Oral · In-Person
The intrinsic antibiotic resistance of environmental bacterial species – a clue to understand the emerging of multi-drug resistant strains
Mihaela Ileana Ionescu · Iuliu Hatieganu University of Medicine and Pharmacy, Romania
The antibiotic resistance of bacterial strains evolves continuously. The nosocomial infections and the infections of immune-compromised patients put a lot of pressure on healthcare professionals. Very often the source…
- Oral · In-Person
Characteristic features of essential oil composition in selected genus of Ocimum sanctum
Prerna Sharma · Guru Gobind Singh College of Pharmacy, India
The main aim of this research is to provide literature of the Ocimum plant, to know the significance of the Ocimum species carried out by pharmacognostical study and experimental design for GC-MS. Ocimum genus is very…
- Oral · In-Person
Intranasal drug delivery: Perillyl Alcohol/NEO100 for glioblastoma leads the way
Axel H Schonthal · University of Southern California, United States
Malignancies located in the brain are difficult to treat, because most therapeutic agents are unable to enter the brain parenchyma from the circulation, due to the obstacle placed by the blood-brain barrier (BBB).…
- Oral · In-Person
Development and characterization of salbutamol sulfate dry powder inhaler formulations for asthma management
Aysu Yurdasiper · Ege University, Turkey
Asthma is a chronic disease that causes inflammation of the airways and makes it difficult to breathe. The best way to manage asthma is to avoid triggers, take medication to prevent symptoms, and control asthma attacks.…
- Oral · In-Person
A new approach based on glycyrrhizic acid for allergen delivery in allergen-specific therapy
Ekaterina Pashkina · Research Institute of Fundamental and Clinical Immunology, Russian Federation
The most effective method of treating allergic diseases is allergen-specific immunotherapy (SIT). To reduce the risk of side effects and improve the delivery of allergens to the mucosa, various delivery systems such as…
- Oral · In-Person
An immunoactive polymer mediates nucleic acids delivery for cancer immunotherapy
Fanfei Meng · Purdue University, United States
Since the success of immune checkpoint blockade and chimeric antigen receptor T cell therapy, over a dozen immunotherapies have been approved in the past few years, and thousands of immunotherapeutics are currently in…
- Poster · In-Person
Formulation, development and evaluation of chronotherapeutic drug delivery system for the treatment of Nocturnal Asthma
Keerti Maheshwari · Delhi pharmaceutical sciences research and university, India
Nocturnal asthma mainly known as nighttime asthma, it is mainly occur during sleep. The mechanism of this is related to the circadian rhythms that may influence mediators and inflammatory cells, cholinergic tone and…
- Poster · In-Person
Self-nanoemulsifying drug delivery system (SNEDDS) of apremilast: In-vitro evaluation and pharmacokinetic studies
Ibrahim A. Alsarra · King Saud University, Saudi Arabia
Psoriatic arthritis is an autoimmune disease of the joints; it can lead to persistent inflammation, joint damage and disability. Apremilast (APR) was the first FDA-approved oral anti-psoriatic arthritis drug. It APR…
- Poster · In-Person
Antibiotic and phytoconstituent combination loaded gastric floating microsponge for the effective eradication of Helicobacter Pylori infection: Formulation, physicochemical and microbiological assessments
Essa Abdullah Aldulaym · Clinical Pharmacy Student, Saudi Arabia
The present investigation aimed to develop an antibiotic and a phytoconstituent combination loaded gastric floating microsponge for the effective eradication of Helicobacter pylori infection by the synergistic effects…
- Poster · In-Person
The effect of commercially available DPIs on respiratory drug aerosolization
Joanna Chałupka · Nicolaus Copernicus University, Poland
FP (fluticasone propionate) is a synthetic fluorinated cortisol derivative with a strong anti-inflammatory effect. In inhaled form, it is used to treat asthma, and less frequently, to treat COPD. Typically the DPI…
Present your research at PDDS 2027
Abstract submissions for the 2027 program are open · September 13–15, 2027 · Olympia Hotel, Events & Spa, Valencia, Spain.
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Valencia · September 13–15, 2027 · Hybrid · in-person & virtual
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