Arwyn gained his PhD in protein crystallography at Birkbeck College, University of London and undertook postdoctoral positions investigating membrane traffic on the endocytic pathway at the University of Liverpool, Harvard University and the European Molecular Biology Laboratory, in Heidelberg. In 2001 he was appointed as lecturer in at the Cardiff School of Pharmacy and Pharmaceutical Sciences at Cardiff University where he is now Professor in Membrane Traffic and Drug Delivery.
Research projects in his lab fall under themes of cancer cell biology, endocytosis and drug delivery. A major scientific objective is linking fundamental endocytosis research to better understand the cellular delivery of drug delivery vectors including antibodies targeting plasma membrane receptors. He actively collaborates with a number of national and international groups including his recent strong involvement with COMPACT (http://www.compact-research.org/), an academic/industrial drug delivery consortium collaborating on the Optimisation of Macromolecular Pharmaceutical Access to Cellular Targets.