Ulo Langel

Speaker for pharma events-Ulo Langel

Title: Transfection by cell-penetrating peptides

Ulo Langel

Stockholm University, Sweden

Biography

Ülo Langel is a Professor at the Department of Neurochemistry, Stockholm University, and at the Institute of Technology, Tartu University. Prof. Langel has been selected as a Fellow Member of International Neuropeptide Society (1995), and is a member of Academia Europeaea. He is a coauthor of more than 400 scientific articles and 20 approved patents or patent applications. 

Abstract

Recent data on mechanisms and applications of transfection strategies by cell penetrating peptides (CPP) are summarized on the variety of different oligonucleotide cargoes including plasmid, antisense and siRNA oligonucleotides. Introduction of PepFect and NickFect technologies for oligonucleotide transfection by transportan-based cell-penetrating peptides in vitro and in vivo is described. 403. Kurrikoff,K., Gestin,M., and Langel,Ü. (2016) Recent in vivo advances in cell-penetrating peptide-assisted drug delivery. Expert Opinion on Drug Delivery, 13(3), 373-387.